2型糖尿病相关患者决策辅助的有效性是什么?系统评价的二次分析。

Sandhya Goge, Christopher Tran, Krystina B Lewis, Meg Carley, Carol Bennett, Dawn Stacey
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引用次数: 0

摘要

患者决策辅助(ptda)是基于证据的干预措施,以帮助人们面对困难的医疗保健决定。对于面临糖尿病相关决定的人来说,它们的有效性知之甚少。方法:对2024年Cochrane回顾ptda的随机对照试验进行二次分析,比较糖尿病筛查、预防或治疗的决策辅助与常规护理(如患者教育、不干预)。两位审稿人独立筛选引文、提取数据并评估研究质量。主要结果:决策质量和决策过程。对类似的结果测量进行了荟萃分析。结果:在209项随机对照试验中,11项符合条件的研究评估了糖尿病ptda的治疗(n=7)、筛查(n=3)和预防(n=1)。在2型糖尿病患者中,常见的决定是加强糖尿病治疗(n=4)和开始他汀类药物治疗(n=3)。与常规护理组相比,PtDA组患者对风险的认知增加(MD为16.06,95%CI为8.38 ~ 23.75),价值更清晰(MD为-7.43,95%CI为-13.23 ~ -1.63),但对风险的准确认知无差异。在去除高风险偏倚研究后,ptda导致较少的患者不了解他们的选择(MD -6.38;95%CI -9.58至-3.19),更多的参与者开始使用新药物(RR 1.65, 95%CI 1.06至2.56)。六项研究测量了所选方案的依从性:一项报告了PtDA与常规治疗相比更高的依从性,另一项报告了更低的依从性,其余四项报告没有差异。结论:接受ptda治疗的患者可以提高他们的知识水平,更清楚地了解自己的价值观,同时更有可能开始新的药物治疗。未来的研究可以加强这些发现的确定性,并探索ptda在慢性疾病中的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
What is the Effectiveness of Type 2 Diabetes Related Patient Decision Aids? Secondary Analysis of a Systematic Review.

Introduction: Patient decision aids (PtDAs) are evidence-based interventions to help people faced with difficult healthcare decisions. Little is known about their effectiveness in people facing diabetes related decisions.

Methods: Secondary analysis of RCTs from 2024 Cochrane review of PtDAs, comparing decisions aids on diabetes screening, prevention or treatment to usual care (e.g., patient education, no intervention). Two reviewers independently screened citations, extracted data and assessed study quality.

Primary outcomes: quality of the decision and decision-making process. Meta-analyses were conducted for similar outcome measures.

Results: Of 209 RCTs, 11 eligible studies evaluated diabetes PtDAs for treatment (n=7), screening (n=3) and prevention (n=1). Common decisions were about diabetes treatment intensification (n=4) and statin initiation (n=3), in people with type 2 diabetes. Compared to usual care, PtDA group reported increased knowledge (MD 16.06, 95%CI 8.38 to23.75) and clearer values (MD -7.43, 95%CI -13.23 to -1.63) and no difference in accurate risk perceptions. After removing high risk of bias studies, PtDAs led to fewer patients feeling uninformed about their options (MD -6.38; 95%CI -9.58 to -3.19) and more participants starting new medications (RR 1.65, 95%CI 1.06 to 2.56). Six studies measured adherence to a chosen option: one reported greater adherence while another reported lower adherence in PtDA versus usual care and remaining four reported no difference.

Conclusion: Patients given PtDAs can improve their knowledge, feel informed and clearer about their values, while being more likely to start new medications. Future research can strengthen certainty of these findings and explore PtDAs use within chronic disease.

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