机器学习算法在预测1年创伤性脊髓损伤后再住院中的应用。

IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY
Spinal cord Pub Date : 2025-04-01 Epub Date: 2025-02-15 DOI:10.1038/s41393-024-01055-9
Salma Aly, Yuying Chen, Abdulaziz Ahmed, Huacong Wen, Tapan Mehta
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引用次数: 0

摘要

研究设计:回顾性队列研究。目的:主要目的是开发一种机器学习(ML)模型来预测创伤性脊髓损伤(TSCI)第一年的再住院,并利用初始康复期间获得的数据确定最佳预测因子。第二个目的是预测再住院组的住院时间延长。设置:全美18个SCI模型系统中心。方法:数据从国家脊髓损伤模型系统数据库中检索。参与者根据受伤第一年的再住院情况分为两组。第一年再次住院的患者进一步分为延长住院时间(总住院时间的第75分位数)和非延长住院时间。模型中考虑的变量包括社会人口因素、临床特征和合并症。结果:预测再住院和延长住院时间的最佳分类模型为Random Forest和Adaptive Boosting。两种模型中最重要的预测因子是功能独立程度、美国脊髓损伤协会(ASIA)评分、年龄、从损伤到康复入院的天数和体重指数。此外,对于长期住院,压力损伤作为再住院的原因是最重要的预测因素。结论:功能独立测量(FIM)和ASIA评分是再次住院和延长再住院的关键预测因素。这些发现可能有助于临床医生对患者进行风险评估。此外,将压力损伤确定为延长住院时间的主要预测因素,意味着有针对性地关注与压力损伤相关的再住院的预防措施,提供具体的策略来增强患者的护理和结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Utilization of machine learning algorithm in the prediction of rehospitalization during one-year post traumatic spinal cord injury.

Study design: Retrospective cohort study.

Objective: The primary aim was to develop a machine learning (ML) model to predict rehospitalization during the first year of traumatic spinal cord injury (TSCI) and to identify top predictors using data obtained during initial rehabilitation. The secondary aim was to predict prolonged hospital stay among the rehospitalized group.

Setting: Eighteen SCI Model Systems centers throughout the United States.

Methods: Data were retrieved from the National Spinal Cord Injury Model Systems Database. The participants were divided into 2 groups based on rehospitalization during the first year of injury. Those who experienced rehospitalization during first year were further grouped into prolonged stay (>75th quartile of the total length of stay) or non-prolonged stay. Variables considered in models included socio-demographic factors, clinical characteristics, and comorbidities.

Results: The best performing classification models were Random Forest for predicting rehospitalization and Adaptive Boosting for prolonged stay. The most important predictors in both models were the degree of functional independence, American Spinal Injury Association (ASIA) scores, age, days from injury to rehabilitation admission and body mass index. Additionally, for prolonged stays, pressure injury as a reason for rehospitalization was top predictor.

Conclusion: Functional Independence Measure (FIM) and ASIA scores emerge as key predictors of both rehospitalizations and prolonged rehospitalizations. These findings may assist clinicians in patient risk assessment. Furthermore, the identification of pressure injury as a primary predictor for prolonged stays signifies a targeted focus on preventive measures for pressure injury-related rehospitalizations, offering a specific strategy to enhance patient care and outcomes.

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来源期刊
Spinal cord
Spinal cord 医学-临床神经学
CiteScore
4.50
自引率
9.10%
发文量
142
审稿时长
2 months
期刊介绍: Spinal Cord is a specialised, international journal that has been publishing spinal cord related manuscripts since 1963. It appears monthly, online and in print, and accepts contributions on spinal cord anatomy, physiology, management of injury and disease, and the quality of life and life circumstances of people with a spinal cord injury. Spinal Cord is multi-disciplinary and publishes contributions across the entire spectrum of research ranging from basic science to applied clinical research. It focuses on high quality original research, systematic reviews and narrative reviews. Spinal Cord''s sister journal Spinal Cord Series and Cases: Clinical Management in Spinal Cord Disorders publishes high quality case reports, small case series, pilot and retrospective studies perspectives, Pulse survey articles, Point-couterpoint articles, correspondences and book reviews. It specialises in material that addresses all aspects of life for persons with spinal cord injuries or disorders. For more information, please see the aims and scope of Spinal Cord Series and Cases.
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