{"title":"非进展期艾滋病病毒感染者:更多线索和更多问题。","authors":"Julia Hitschfel, Bruce D Walker","doi":"10.1016/j.medj.2024.10.014","DOIUrl":null,"url":null,"abstract":"<p><p>Viremic non-progressors are a unique subset of untreated people living with HIV who remarkably maintain high CD4<sup>+</sup> T cell counts despite continuous high plasma viral loads. To better understand this rare phenotype, Bayón-Gil et al. explored host genetic and immunologic factors distinguishing viremic non-progressors from individuals with progressive disease.</p>","PeriodicalId":29964,"journal":{"name":"Med","volume":"6 2","pages":"100537"},"PeriodicalIF":12.8000,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"HIV viremic non-progressors: More clues and more questions.\",\"authors\":\"Julia Hitschfel, Bruce D Walker\",\"doi\":\"10.1016/j.medj.2024.10.014\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Viremic non-progressors are a unique subset of untreated people living with HIV who remarkably maintain high CD4<sup>+</sup> T cell counts despite continuous high plasma viral loads. To better understand this rare phenotype, Bayón-Gil et al. explored host genetic and immunologic factors distinguishing viremic non-progressors from individuals with progressive disease.</p>\",\"PeriodicalId\":29964,\"journal\":{\"name\":\"Med\",\"volume\":\"6 2\",\"pages\":\"100537\"},\"PeriodicalIF\":12.8000,\"publicationDate\":\"2025-02-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Med\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.medj.2024.10.014\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Med","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.medj.2024.10.014","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
HIV viremic non-progressors: More clues and more questions.
Viremic non-progressors are a unique subset of untreated people living with HIV who remarkably maintain high CD4+ T cell counts despite continuous high plasma viral loads. To better understand this rare phenotype, Bayón-Gil et al. explored host genetic and immunologic factors distinguishing viremic non-progressors from individuals with progressive disease.
期刊介绍:
Med is a flagship medical journal published monthly by Cell Press, the global publisher of trusted and authoritative science journals including Cell, Cancer Cell, and Cell Reports Medicine. Our mission is to advance clinical research and practice by providing a communication forum for the publication of clinical trial results, innovative observations from longitudinal cohorts, and pioneering discoveries about disease mechanisms. The journal also encourages thought-leadership discussions among biomedical researchers, physicians, and other health scientists and stakeholders. Our goal is to improve health worldwide sustainably and ethically.
Med publishes rigorously vetted original research and cutting-edge review and perspective articles on critical health issues globally and regionally. Our research section covers clinical case reports, first-in-human studies, large-scale clinical trials, population-based studies, as well as translational research work with the potential to change the course of medical research and improve clinical practice.