IF 1.9 4区 医学 Q3 RESPIRATORY SYSTEM
Colin J. Crooks, Dominick Shaw, Timothy R. Card, Iain Au-Yong, Yutaro Higashi, Elisabetta Giannotti, Andrew W. Fogarty
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引用次数: 0

摘要

背景 胸片通常用于诊断目的。它们还可以量化疾病的严重程度。本分析检验了以下假设:Covid-19 感染患者的胸片不透明与呼吸生理状态和全身炎症指标之间存在关联。 方法 将胸片不透明的数据与同时测量的氧需求量和饱和度以及血清 C 反应蛋白进行比较。 结果 628 人的数据可用。胸片不透明的中位数为 20%(四分位间范围为 5-45)。这与 SFR(血氧饱和度/补充氧)相关,其 r 值为 -0.38(95% 置信区间 CI:-0.45 至 -31):-0.38(95% 置信区间 CI:-0.45 至 -31,皮尔逊相关系数)和 CRP(+0.33;95% CI:+0.24 至 +0.41,皮尔逊相关系数)。 结论 胸片不透明评分与 Covid-19 感染患者的呼吸生理状态和全身炎症水平相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The Linear Association of Chest Radiograph Opacification With Both Respiratory Physiology and Systemic Inflammation in Hospital In-Patients With Covid-19 Infection

The Linear Association of Chest Radiograph Opacification With Both Respiratory Physiology and Systemic Inflammation in Hospital In-Patients With Covid-19 Infection

Background

Chest radiographs are generally used for diagnostic purposes. They also have potential to quantify disease severity. This analysis tested the hypothesis that there was an association between chest radiograph opacification and measures of respiratory physiological status and systemic inflammation in patients with Covid-19 infection.

Methods

Data on chest radiograph opacification were compared with concurrent measures of oxygen requirements and saturation and serum C-reactive protein.

Results

Data were available from 628 individuals. The median opacification on chest radiographs was 20% (interquartile range 5–45). This was associated both SFR (oxygen saturation/supplementary oxygen) with an r value of −0.38 (95% confidence intervals CI: −0.45 to −31, Pearson's correlation coefficient) and CRP (+0.33; 95% CI: +0.24 to +0.41, Pearson's correlation coefficient).

Conclusion

Chest radiograph opacification scores are associated with both respiratory physiology status and systemic inflammation levels in patients with Covid-19 infection.

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来源期刊
Clinical Respiratory Journal
Clinical Respiratory Journal 医学-呼吸系统
CiteScore
3.70
自引率
0.00%
发文量
104
审稿时长
>12 weeks
期刊介绍: Overview Effective with the 2016 volume, this journal will be published in an online-only format. Aims and Scope The Clinical Respiratory Journal (CRJ) provides a forum for clinical research in all areas of respiratory medicine from clinical lung disease to basic research relevant to the clinic. We publish original research, review articles, case studies, editorials and book reviews in all areas of clinical lung disease including: Asthma Allergy COPD Non-invasive ventilation Sleep related breathing disorders Interstitial lung diseases Lung cancer Clinical genetics Rhinitis Airway and lung infection Epidemiology Pediatrics CRJ provides a fast-track service for selected Phase II and Phase III trial studies. Keywords Clinical Respiratory Journal, respiratory, pulmonary, medicine, clinical, lung disease, Abstracting and Indexing Information Academic Search (EBSCO Publishing) Academic Search Alumni Edition (EBSCO Publishing) Embase (Elsevier) Health & Medical Collection (ProQuest) Health Research Premium Collection (ProQuest) HEED: Health Economic Evaluations Database (Wiley-Blackwell) Hospital Premium Collection (ProQuest) Journal Citation Reports/Science Edition (Clarivate Analytics) MEDLINE/PubMed (NLM) ProQuest Central (ProQuest) Science Citation Index Expanded (Clarivate Analytics) SCOPUS (Elsevier)
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