Thuy-Tien N. Nguyen , Hirotaka Tsukada , Gregory R. James , Iain A. Rankin , Louise McMenemy , John Breeze , Spyros D. Masouros
{"title":"皮肤爆炸穿透伤研究的实验模型与仿真","authors":"Thuy-Tien N. Nguyen , Hirotaka Tsukada , Gregory R. James , Iain A. Rankin , Louise McMenemy , John Breeze , Spyros D. Masouros","doi":"10.1016/j.jmbbm.2025.106936","DOIUrl":null,"url":null,"abstract":"<div><div>Energised fragments from explosions are the most common wounding mechanism in conflicts and terrorist attacks. Skin covers the vast majority of the human body and is therefore the first anatomical component to be penetrated by fragments, however, its resistance to penetration largely has not been taken into account in models of injury. In this study, an experimental model for ballistic testing of skin is established and a suitable skin simulant for studying resistance to penetration is determined. Fragment-simulating projectiles were fired at human cadaveric skin and skin-simulant candidates. Tissue responses were quantified by evaluating the impact velocity at 50% risk of skin penetration and perforation, and the depth of penetration in cadaveric tissue or skin-simulant candidates. The results identified a 1.5-mm-thick butyl rubber as a suitable skin simulant across the range of threats tested. The findings can help refine assessment of protective systems and predictive models of injury in an effort to improve outcomes of fragment-penetrating injuries.</div></div>","PeriodicalId":380,"journal":{"name":"Journal of the Mechanical Behavior of Biomedical Materials","volume":"165 ","pages":"Article 106936"},"PeriodicalIF":3.3000,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Experimental model and simulant for studying blast penetrating injury to the skin\",\"authors\":\"Thuy-Tien N. Nguyen , Hirotaka Tsukada , Gregory R. James , Iain A. Rankin , Louise McMenemy , John Breeze , Spyros D. Masouros\",\"doi\":\"10.1016/j.jmbbm.2025.106936\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Energised fragments from explosions are the most common wounding mechanism in conflicts and terrorist attacks. Skin covers the vast majority of the human body and is therefore the first anatomical component to be penetrated by fragments, however, its resistance to penetration largely has not been taken into account in models of injury. In this study, an experimental model for ballistic testing of skin is established and a suitable skin simulant for studying resistance to penetration is determined. Fragment-simulating projectiles were fired at human cadaveric skin and skin-simulant candidates. Tissue responses were quantified by evaluating the impact velocity at 50% risk of skin penetration and perforation, and the depth of penetration in cadaveric tissue or skin-simulant candidates. The results identified a 1.5-mm-thick butyl rubber as a suitable skin simulant across the range of threats tested. The findings can help refine assessment of protective systems and predictive models of injury in an effort to improve outcomes of fragment-penetrating injuries.</div></div>\",\"PeriodicalId\":380,\"journal\":{\"name\":\"Journal of the Mechanical Behavior of Biomedical Materials\",\"volume\":\"165 \",\"pages\":\"Article 106936\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2025-02-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the Mechanical Behavior of Biomedical Materials\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1751616125000529\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Mechanical Behavior of Biomedical Materials","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1751616125000529","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
Experimental model and simulant for studying blast penetrating injury to the skin
Energised fragments from explosions are the most common wounding mechanism in conflicts and terrorist attacks. Skin covers the vast majority of the human body and is therefore the first anatomical component to be penetrated by fragments, however, its resistance to penetration largely has not been taken into account in models of injury. In this study, an experimental model for ballistic testing of skin is established and a suitable skin simulant for studying resistance to penetration is determined. Fragment-simulating projectiles were fired at human cadaveric skin and skin-simulant candidates. Tissue responses were quantified by evaluating the impact velocity at 50% risk of skin penetration and perforation, and the depth of penetration in cadaveric tissue or skin-simulant candidates. The results identified a 1.5-mm-thick butyl rubber as a suitable skin simulant across the range of threats tested. The findings can help refine assessment of protective systems and predictive models of injury in an effort to improve outcomes of fragment-penetrating injuries.
期刊介绍:
The Journal of the Mechanical Behavior of Biomedical Materials is concerned with the mechanical deformation, damage and failure under applied forces, of biological material (at the tissue, cellular and molecular levels) and of biomaterials, i.e. those materials which are designed to mimic or replace biological materials.
The primary focus of the journal is the synthesis of materials science, biology, and medical and dental science. Reports of fundamental scientific investigations are welcome, as are articles concerned with the practical application of materials in medical devices. Both experimental and theoretical work is of interest; theoretical papers will normally include comparison of predictions with experimental data, though we recognize that this may not always be appropriate. The journal also publishes technical notes concerned with emerging experimental or theoretical techniques, letters to the editor and, by invitation, review articles and papers describing existing techniques for the benefit of an interdisciplinary readership.