免疫性血小板减少性紫癜患者的血栓栓塞事件1例报告。

IF 0.8 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL
Maimoona Nazar, Nasir Ashraf, Laiba Sultan, Laiba Sultan
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引用次数: 0

摘要

免疫性血小板减少性紫癜(ITP)是一种以血小板计数低为特征的自身免疫性疾病,这是由于骨髓中巨核细胞产生减少和脾脏中自身抗体的产生导致血小板破坏。患有自身免疫性疾病的个体极易发生肺栓塞。本病例涉及一名患有ITP的39岁女性,她发展为血栓栓塞。对血栓形成前危险因素的全面调查,包括肥胖、吸烟、血栓栓塞家族史和itp相关的干预措施,如长期使用皮质类固醇或脾切除术,除了患者接受皮质类固醇治疗的历史外,结果不显著。尽管血栓栓塞(TE)和ITP的发病机制不同,但ITP患者最近发生的TE事件已被观察到。本报告强调ITP中潜在的危及生命的并发症,旨在探讨其原因和发病机制,以确保优化患者护理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Thromboembolic event in a patient of immune thrombocytopenic purpura: a case report.

Immune Thrombocytopenia Purpura (ITP) is an autoimmune disorder characterised by a low blood platelet count, which is attributed to both decreased megakaryocyte production in the bone marrow and the generation of autoantibodies causing platelet destruction in the spleen. Individuals with autoimmune conditions are highly susceptible to pulmonary embolism. This case involves a 39-year-old female with ITP who developed thromboembolisms. A comprehensive investigation into prothrombotic risk factors, including obesity, smoking, family history of thromboembolism, and ITP-related interventions such as prolonged corticosteroid use or splenectomy, revealed insignificant results, except for the patient's history of receiving corticosteroid therapy. Despite the disparate pathogenesis of thromboembolism (TE) and ITP, recent events of TE in ITP patients have been observed. This report underscores the potential lifethreatening complications in ITP and aims to explore their causes and pathogenesis for ensuring optimised patient care.

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来源期刊
CiteScore
1.10
自引率
11.10%
发文量
983
审稿时长
3-6 weeks
期刊介绍: Primarily being a medical journal, JPMA publishes scholarly research focusing on the various fields in the areas of health and medical education. It publishes original research describing recent advances in health particularly clinical studies, clinical trials, assessments of pathogens of diagnostic importance, medical genetics and epidemiological studies. Review articles highlighting importance of various issues in the domain of public health, drug research and medical education are also accepted. As a leading journal of South Asia, JPMA remains cognizant of the recent advances in the rapidly growing fields of biomedical sciences, it invites and encourages scholars to write short reviews and invited editorials on the emerging issues. We particularly aim to promote health standards of developing countries by encouraging manuscript submissions on issues affecting the public health and health delivery services.
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