唐氏综合症是鼻泪管支架植入术后发生角膜溃疡的危险因素。

IF 1.2 4区医学 Q3 OPHTHALMOLOGY

Journal of Aapos Pub Date : 2025-04-01 DOI:10.1016/j.jaapos.2025.104126

Brittany Marks BA , Michael A. Puente MD

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引用次数: 0

摘要

鼻泪管支架常用于治疗先天性鼻泪管阻塞（NLDO）。很少，角膜溃疡可能在支架置入后发生。在我们机构33个月的时间里，253例先天性NLDO患者放置了349个单管支架，其中4个支架（1.1%）导致角膜溃疡。3例发生在唐氏综合征儿童中（n = 35）；1例发生于回顾性诊断为神经营养性角膜炎的儿童。这3例患者与其他患者相比，唐氏综合征患儿角膜溃疡形成的相对风险有统计学意义的增加(9% vs 0.46%；相对危险度= 18.68；P = 0.0102)。

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Down syndrome is a risk factor for developing corneal ulcers following nasolacrimal duct stenting

Nasolacrimal duct stents are often used to treat congenital nasolacrimal duct obstruction (NLDO). Rarely, corneal ulcers may develop following stent placement. Of the 349 monocanalicular stents placed in 253 patients with congenital NLDO over a period of 33 months at our institution, 4 stents (1.1%) resulted in corneal ulcers. Three occurred in children with Down syndrome (n = 35); 1 occurred in a child retroactively diagnosed with neurotrophic keratitis. The 3 cases indicate a statistically significant increased relative risk of corneal ulcer formation in children with Down syndrome compared with the remaining patients (9% vs 0.46%; relative risk = 18.68; P = 0.0102).

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来源期刊

Journal of Aapos 医学-小儿科

CiteScore

2.40

自引率

12.50%

发文量

159

审稿时长

55 days

期刊介绍： Journal of AAPOS presents expert information on children''s eye diseases and on strabismus as it affects all age groups. Major articles by leading experts in the field cover clinical and investigative studies, treatments, case reports, surgical techniques, descriptions of instrumentation, current concept reviews, and new diagnostic techniques. The Journal is the official publication of the American Association for Pediatric Ophthalmology and Strabismus.