Haoran Xing, Xiaolei Liu, Yingying Zhang, Jie Wu, Mier Li, Hong Ye, Yu Ding, Weiwei Wang, Zhong Zheng, Tianhao Bao
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Advances in repetitive transcranial magnetic stimulation in the treatment of treatment-resistant depression: a comprehensive review.
Major depressive disorder is a common mental disorder, and a significant number of patients exhibit poor response to conventional antidepressant treatments, known as treatment-resistant depression (TRD). However, the definition of TRD globally remains unclear, impeding clinical research, treatment development, outcome implementation, and policy-making. A wealth of research confirms that rTMS demonstrates promising efficacy in TRD. This paper elucidates the definition of TRD, summarizes potential targets of rTMS for treating TRD, comprehensively elaborates on the unique mechanisms, efficacy, and side effects of rTMS in treating TRD, and outlines considerations for special populations receiving rTMS treatment for TRD as well as other treatment modalities for TRD. Through these studies, we aim to provide more scientifically grounded recommendations for patients undergoing rTMS treatment for TRD.
期刊介绍：
Reviews in the Neurosciences provides a forum for reviews, critical evaluations and theoretical treatment of selective topics in the neurosciences. The journal is meant to provide an authoritative reference work for those interested in the structure and functions of the nervous system at all levels of analysis, including the genetic, molecular, cellular, behavioral, cognitive and clinical neurosciences. Contributions should contain a critical appraisal of specific areas and not simply a compilation of published articles.
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