使用氯前列醇和黄体酮注射的大鼠的发情周期同步方案。

IF 1.3 4区农林科学 Q2 VETERINARY SCIENCES

Laboratory Animals Pub Date : 2025-06-01 Epub Date: 2025-02-13 DOI:10.1177/00236772241309754

Sophia Potapova, Viktor Stratilov, Oleg Vetrovoy, Diana Safarova, Ekaterina Tyulkova

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引用次数: 0

摘要

本研究探讨了氯前列醇（Cl）和孕酮（Pg）联合注射对雌性大鼠同步发情的影响。进行了一系列全面的实验，以探索激素注射对随后生殖行为的影响。这项研究包括将大鼠分成不同的组，每组注射特定的氯、Pg或它们的组合。我们观察到Cl + Pg + Cl组在最后一次注射Cl后第一天内受孕率为100%。这一发现强调了所采用的方案的显著有效性，导致大量雌性大鼠在同一天迅速开始怀孕。

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Oestrous cycle synchronization protocols in rats using cloprostenol and progesterone injections.

This study investigated the effectiveness of combining cloprostenol (Cl) and progesterone (Pg) injections for oestrous synchronization in female rats. A comprehensive series of experiments was conducted to explore the impact of hormonal injections on subsequent reproductive behaviour. The study involved dividing rats into distinct groups, with each group subjected to specific injections of either Cl, Pg, or their combinations. We observed a 100% conception efficiency within the first day after the last Cl injection in the Cl + Pg + Cl group. This finding underscores the remarkable effectiveness of the employed protocol, resulting in a rapid initiation of pregnancy in a substantial number of female rats on the same day.

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来源期刊

Laboratory Animals 生物-动物学

CiteScore

4.90

自引率

8.30%

发文量

审稿时长

6-12 weeks

期刊介绍： The international journal of laboratory animal science and welfare, Laboratory Animals publishes peer-reviewed original papers and reviews on all aspects of the use of animals in biomedical research. The journal promotes improvements in the welfare or well-being of the animals used, it particularly focuses on research that reduces the number of animals used or which replaces animal models with in vitro alternatives.