口腔卫生不良：幽门螺杆菌感染的潜在危险因素。

IF 3.2 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

International dental journal Pub Date : 2025-02-12 DOI:10.1016/j.identj.2025.01.001

Xiao Zhao , Xiao She , Haiyan Yang , Ziqin Zeng , Weicheng Zhi , Yan Jing , Lei Dong , Jun Gong , Haitao Guan , Ping Zhao

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引用次数: 0

摘要

背景：幽门螺杆菌（h.p ylori）最初通过口腔进入人体。口腔健康与幽门螺杆菌感染状态之间的相关性在科学文献中仍然是一个有争议的话题。为了阐明幽门螺杆菌感染与口腔卫生状况和习惯之间的关系，我们对消化不良患者进行了一项横断面研究。方法：收集2023年5 - 8月在西安交通大学第二附属医院接受13c -尿素呼气试验（13C-UBT）和幽门螺杆菌抗原试验（HPS）检测胃和口腔幽门螺杆菌感染的362例有消化不良症状的患者的资料。参与者完成关于社会人口特征、病史、消化不良症状、口腔卫生状况和口腔卫生习惯的问卷调查。此外，参与者还接受了口腔检查，包括简化口腔卫生指数（OHI-S）、碎屑指数（DI-S）、简化牙石指数（CI-S）和蛀牙、缺牙和补牙（DMFT）评分。结果：口腔幽门螺杆菌感染状况与性别、体重指数（BMI）、教育程度、口腔卫生习惯、居住地或收入无关。考虑到性别和体重指数，年龄超过60岁显著增加发生口腔幽门螺杆菌感染的风险（OR = 5.51, 95% CI: 1.56-19.46, P = 0.0081），而缺乏抗生素使用史被确定为一个保护因素（OR = 0.45, 95% CI: 0.26-0.77, P = 0.0036）。此外，DMFT bb0 4 （OR = 2.54, 95% CI: 1.15 ~ 5.61, P = 0.0210）、0.67 < OHI-S≤1.33 （OR = 1.98, 95% CI: 1.09 ~ 3.59, P = 0.0246）和0.33结论：我们的研究结果表明口腔健康与口腔幽门螺杆菌感染之间存在关系，提示口腔卫生不良可能与口腔幽门螺杆菌定殖风险增加有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Poor Oral Hygiene: A Hidden Risk Factor for Helicobacter pylori Infection

Background

Helicobacter pylori (H. pylori) initially enters the human body through the mouth. The correlation between oral health and H. pylori infection status remains a topic of debate in the scientific literature. To elucidate the relationships between H. pylori infection and oral hygiene status and habits, we performed a cross-sectional study among dyspeptic patients.

Methods

Data were collected from 362 subjects with dyspepsia symptoms who underwent the 13C-urea breath test (13C-UBT) and the H. pylori antigen test (HPS) to test for gastric and oral H. pylori infections between May and August 2023 at The Second Affiliated Hospital of Xi'an Jiaotong University. The participants completed questionnaires on sociodemographic characteristics, medical history, dyspepsia symptoms, oral hygiene status, and oral hygiene practices. In addition, the participants underwent oral exams involving the simplified oral hygiene index (OHI-S), the Debris index (DI-S), the simplified calculus index (CI-S), and the decayed, missing, and filled teeth (DMFT) score.

Results

Oral H. pylori infection status was not associated with sex, body mass index (BMI), education, oral hygiene habits, place of residence, or income. Considering sex and BMI, being over 60 years of age significantly increased the risk of developing oral H. pylori infection (OR = 5.51, 95% CI: 1.56-19.46, P = .0081), whereas a lack of history of antibiotic use was identified as a protective factor (OR = 0.45, 95% CI: 0.26-0.77, P = .0036). Additionally, DMFT >4 (OR = 2.54, 95% CI: 1.15-5.61, P = .0210), 0.67 < OHI-S ≤ 1.33 (OR = 1.98, 95% CI: 1.09-3.59, P = .0246), and 0.33<DI≤0.67 (OR = 2.00, 95% CI: 1.11-3.62, P = .0215) were identified as independent risk factors for oral H. pylori infection.

Conclusion

The results of our research indicate a relationship between oral health and oral H. pylori infection, suggesting that poor oral hygiene may be associated with an increased risk of oral H. pylori colonization.

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来源期刊

International dental journal 医学-牙科与口腔外科

CiteScore

4.80

自引率

6.10%

发文量

159

审稿时长

63 days

期刊介绍： The International Dental Journal features peer-reviewed, scientific articles relevant to international oral health issues, as well as practical, informative articles aimed at clinicians.