{"title":"电子烟使用对牙周健康的影响：系统回顾和荟萃分析。","authors":"Rajpal Tattar, Joshua Jackson, Richard Holliday","doi":"10.1038/s41432-025-01119-6","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Electronic Nicotine Delivery Systems (ENDS, e-cigarettes) are a popular alternative to traditional tobacco smoking.</p><p><strong>Objective: </strong>To evaluate the effect of ENDS use on periodontal health.</p><p><strong>Methods: </strong>A protocol was published in accordance with PRISMA standards. Subjects with periodontal health, gingivitis and periodontitis were included. Reviews, case reports, letters, abstracts, narratives and expert opinions were excluded. Databases searched included PubMed, Embase, Web of Science, CINAHL Plus, and Dentistry & Oral Sciences Source up until February 2024. Risk of bias was evaluated using the Newcastle-Ottawa Scale, ROBINS-I and the RoB 2 tools.</p><p><strong>Results: </strong>40 eligible studies were included. Smokers had poorer clinical outcomes than ENDS users and non-smokers/former smokers, apart from bleeding on probing and gingival indices. There was no difference between ENDS users and non-smokers/former smokers in markers of periodontal destruction (pocket probing depths/marginal bone loss). ENDS users had higher plaque scores than non-smokers/former smokers. ENDS use leads to unique microbial changes compared to tobacco smokers and higher pro-inflammatory markers compared to non-smokers/former smokers.</p><p><strong>Conclusion: </strong>Within the limitations of the included studies which are at high risk of bias, we found evidence that ENDS use had some impact on periodontal parameters compared to non-smokers/former smokers. Tobacco smokers had consistently worst outcomes. REGISTRATION PROSPERO 2024: CRD42024496560.</p>","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The impact of e-cigarette use on periodontal health: a systematic review and meta-analysis.\",\"authors\":\"Rajpal Tattar, Joshua Jackson, Richard Holliday\",\"doi\":\"10.1038/s41432-025-01119-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Electronic Nicotine Delivery Systems (ENDS, e-cigarettes) are a popular alternative to traditional tobacco smoking.</p><p><strong>Objective: </strong>To evaluate the effect of ENDS use on periodontal health.</p><p><strong>Methods: </strong>A protocol was published in accordance with PRISMA standards. Subjects with periodontal health, gingivitis and periodontitis were included. Reviews, case reports, letters, abstracts, narratives and expert opinions were excluded. Databases searched included PubMed, Embase, Web of Science, CINAHL Plus, and Dentistry & Oral Sciences Source up until February 2024. Risk of bias was evaluated using the Newcastle-Ottawa Scale, ROBINS-I and the RoB 2 tools.</p><p><strong>Results: </strong>40 eligible studies were included. Smokers had poorer clinical outcomes than ENDS users and non-smokers/former smokers, apart from bleeding on probing and gingival indices. There was no difference between ENDS users and non-smokers/former smokers in markers of periodontal destruction (pocket probing depths/marginal bone loss). ENDS users had higher plaque scores than non-smokers/former smokers. ENDS use leads to unique microbial changes compared to tobacco smokers and higher pro-inflammatory markers compared to non-smokers/former smokers.</p><p><strong>Conclusion: </strong>Within the limitations of the included studies which are at high risk of bias, we found evidence that ENDS use had some impact on periodontal parameters compared to non-smokers/former smokers. Tobacco smokers had consistently worst outcomes. 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引用次数: 0
摘要
背景：电子尼古丁传递系统（ENDS，电子烟）是传统吸烟的一种流行替代品。目的：评价ENDS的使用对牙周健康的影响。方法：按照PRISMA标准发布治疗方案。研究对象包括牙周健康、牙龈炎和牙周炎患者。综述、病例报告、信函、摘要、叙述和专家意见被排除在外。检索的数据库包括PubMed， Embase, Web of Science， CINAHL Plus和Dentistry & Oral Sciences Source，截止到2024年2月。使用纽卡斯尔-渥太华量表、ROBINS-I和rob2工具评估偏倚风险。结果：纳入了40项符合条件的研究。除了牙诊和牙龈指数出血外，吸烟者的临床结果比ENDS使用者和非吸烟者/前吸烟者差。ENDS使用者与非吸烟者/前吸烟者在牙周破坏标志物（牙袋探测深度/边缘骨质流失）方面没有差异。ENDS使用者的斑块评分高于非吸烟者/前吸烟者。与吸烟者相比，终端的使用导致了独特的微生物变化，与非吸烟者/前吸烟者相比，终端的使用导致了更高的促炎标志物。结论：在纳入的高偏倚风险研究的局限性内，我们发现与非吸烟者/前吸烟者相比，使用ENDS对牙周参数有一定影响的证据。吸烟者的结果一直最糟糕。注册prospero 2024: crd42024496560。
The impact of e-cigarette use on periodontal health: a systematic review and meta-analysis.
Background: Electronic Nicotine Delivery Systems (ENDS, e-cigarettes) are a popular alternative to traditional tobacco smoking.
Objective: To evaluate the effect of ENDS use on periodontal health.
Methods: A protocol was published in accordance with PRISMA standards. Subjects with periodontal health, gingivitis and periodontitis were included. Reviews, case reports, letters, abstracts, narratives and expert opinions were excluded. Databases searched included PubMed, Embase, Web of Science, CINAHL Plus, and Dentistry & Oral Sciences Source up until February 2024. Risk of bias was evaluated using the Newcastle-Ottawa Scale, ROBINS-I and the RoB 2 tools.
Results: 40 eligible studies were included. Smokers had poorer clinical outcomes than ENDS users and non-smokers/former smokers, apart from bleeding on probing and gingival indices. There was no difference between ENDS users and non-smokers/former smokers in markers of periodontal destruction (pocket probing depths/marginal bone loss). ENDS users had higher plaque scores than non-smokers/former smokers. ENDS use leads to unique microbial changes compared to tobacco smokers and higher pro-inflammatory markers compared to non-smokers/former smokers.
Conclusion: Within the limitations of the included studies which are at high risk of bias, we found evidence that ENDS use had some impact on periodontal parameters compared to non-smokers/former smokers. Tobacco smokers had consistently worst outcomes. REGISTRATION PROSPERO 2024: CRD42024496560.
期刊介绍：
Evidence-Based Dentistry delivers the best available evidence on the latest developments in oral health. We evaluate the evidence and provide guidance concerning the value of the author''s conclusions. We keep dentistry up to date with new approaches, exploring a wide range of the latest developments through an accessible expert commentary. Original papers and relevant publications are condensed into digestible summaries, drawing attention to the current methods and findings. We are a central resource for the most cutting edge and relevant issues concerning the evidence-based approach in dentistry today. Evidence-Based Dentistry is published by Springer Nature on behalf of the British Dental Association.
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