开放性脊柱裂后脑疝的产前晚期发育。

IF 1.6 3区 医学 Q3 OBSTETRICS & GYNECOLOGY
Denise Araujo Lapa, Shivani Rangwala, Bassel Zebian, Matthew Brown, Jason Chu, Ramen H Chmait
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引用次数: 0

摘要

简介:我们描述了4例最初被认为是“闭合性”缺陷的开放性脊柱裂,其中一系列产前超声检查记录了妊娠后期囊破裂和Chiari II畸形的发生。病例表现:每例妊娠19-24周的超声检查均显示脊髓囊性病变,包含神经元素,但未见Chiari II型畸形。缺乏后脑疝使他们不适合产前手术修复;但在妊娠24-32周的随访影像显示,囊性病变不再可见或可见但减压,并伴有后脑新发疝。结论:我们建议对假定的“闭合性”脊柱裂进行连续超声监测,因为这些可能实际上是开放性缺陷,只有在怀孕后期才能确诊。这种检测很重要,因为它可能会改变咨询,因为产前修复或计划分娩可能是必要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Late Prenatal Development of Hindbrain Herniation in Open Spina Bifida.

Introduction: We describe 4 cases of open spina bifida initially presumed to be "closed" defects in which serial prenatal ultrasound examinations documented the occurrence of sac rupture and development of Chiari II malformation later in the pregnancy.

Case presentation: In each case, the ultrasound examinations starting from 19 to 24 weeks' gestation, showed spinal cystic lesions containing neural elements but no evidence of Chiari II malformation. The lack of hindbrain herniation rendered them ineligible for prenatal surgical repair, but follow-up imaging at 24-32 weeks' gestation demonstrated the cystic lesions to be no longer visible or visible but decompressed, with the additional development of de novo hindbrain herniation.

Conclusion: We conclude by recommending serial ultrasound surveillance of presumed closed spina bifida as these may be in fact open defects, with confirmatory diagnosis only possible later in pregnancy. This detection is important because it may change counseling since prenatal repair or planned delivery may be warranted.

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来源期刊
Fetal Diagnosis and Therapy
Fetal Diagnosis and Therapy 医学-妇产科学
CiteScore
4.70
自引率
9.10%
发文量
48
审稿时长
6-12 weeks
期刊介绍: The first journal to focus on the fetus as a patient, ''Fetal Diagnosis and Therapy'' provides a wide range of biomedical specialists with a single source of reports encompassing the common discipline of fetal medicine.
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