Mona Lichtblau, Frédéric Lador, Benoit Lechartier, Jana Maria Ellegast, Susanne Pohle, Helga Preiss, Leon Genecand, Carmen Wick, Silvia Ulrich, Lena Reimann
{"title":"肺动脉高压在血液学和肿瘤学疾病领域的应用。","authors":"Mona Lichtblau, Frédéric Lador, Benoit Lechartier, Jana Maria Ellegast, Susanne Pohle, Helga Preiss, Leon Genecand, Carmen Wick, Silvia Ulrich, Lena Reimann","doi":"10.1159/000544126","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Hematological and oncological diseases collectively affect a substantial number of patients. Pulmonary hypertension (PH) is recognized as a potential rare complication associated with these conditions, manifesting in various forms of PH and presenting with a range of symptoms. This review aimed to summarize recent research findings and enhance the understanding of the complex interactions between PH and hemato-oncological diseases.</p><p><strong>Methods: </strong>This narrative review synthesizes recent research findings to explore the interplay between PH and hematological or oncological diseases. A comprehensive search of relevant literature was conducted using PubMed.</p><p><strong>Results: </strong>The complexity of PH in this context arises from its multifactorial etiology, which can include direct effects of malignancies, treatment-related effects, and the impact of disease progression. The variability in how PH presents and progresses in patients with hematological diseases and neoplasms complicates its diagnosis and management. Accurate identification of PH alongside the underlying condition is crucial for enabling optimal treatment and improving overall survival. A multidisciplinary approach is essential to address these challenges effectively.</p><p><strong>Conclusion: </strong>PH in hematologic and oncologic diseases can result from multiple causes. Following a systematic workup, a multidisciplinary approach to management is crucial to ensure optimal treatment and improve survival.</p>","PeriodicalId":21048,"journal":{"name":"Respiration","volume":" ","pages":"1-10"},"PeriodicalIF":3.5000,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pulmonary Hypertension in the Field of Hematological and Oncological Diseases.\",\"authors\":\"Mona Lichtblau, Frédéric Lador, Benoit Lechartier, Jana Maria Ellegast, Susanne Pohle, Helga Preiss, Leon Genecand, Carmen Wick, Silvia Ulrich, Lena Reimann\",\"doi\":\"10.1159/000544126\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Hematological and oncological diseases collectively affect a substantial number of patients. Pulmonary hypertension (PH) is recognized as a potential rare complication associated with these conditions, manifesting in various forms of PH and presenting with a range of symptoms. This review aimed to summarize recent research findings and enhance the understanding of the complex interactions between PH and hemato-oncological diseases.</p><p><strong>Methods: </strong>This narrative review synthesizes recent research findings to explore the interplay between PH and hematological or oncological diseases. A comprehensive search of relevant literature was conducted using PubMed.</p><p><strong>Results: </strong>The complexity of PH in this context arises from its multifactorial etiology, which can include direct effects of malignancies, treatment-related effects, and the impact of disease progression. The variability in how PH presents and progresses in patients with hematological diseases and neoplasms complicates its diagnosis and management. Accurate identification of PH alongside the underlying condition is crucial for enabling optimal treatment and improving overall survival. A multidisciplinary approach is essential to address these challenges effectively.</p><p><strong>Conclusion: </strong>PH in hematologic and oncologic diseases can result from multiple causes. Following a systematic workup, a multidisciplinary approach to management is crucial to ensure optimal treatment and improve survival.</p>\",\"PeriodicalId\":21048,\"journal\":{\"name\":\"Respiration\",\"volume\":\" \",\"pages\":\"1-10\"},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2025-02-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Respiration\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1159/000544126\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"RESPIRATORY SYSTEM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Respiration","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1159/000544126","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
Pulmonary Hypertension in the Field of Hematological and Oncological Diseases.
Introduction: Hematological and oncological diseases collectively affect a substantial number of patients. Pulmonary hypertension (PH) is recognized as a potential rare complication associated with these conditions, manifesting in various forms of PH and presenting with a range of symptoms. This review aimed to summarize recent research findings and enhance the understanding of the complex interactions between PH and hemato-oncological diseases.
Methods: This narrative review synthesizes recent research findings to explore the interplay between PH and hematological or oncological diseases. A comprehensive search of relevant literature was conducted using PubMed.
Results: The complexity of PH in this context arises from its multifactorial etiology, which can include direct effects of malignancies, treatment-related effects, and the impact of disease progression. The variability in how PH presents and progresses in patients with hematological diseases and neoplasms complicates its diagnosis and management. Accurate identification of PH alongside the underlying condition is crucial for enabling optimal treatment and improving overall survival. A multidisciplinary approach is essential to address these challenges effectively.
Conclusion: PH in hematologic and oncologic diseases can result from multiple causes. Following a systematic workup, a multidisciplinary approach to management is crucial to ensure optimal treatment and improve survival.
期刊介绍:
''Respiration'' brings together the results of both clinical and experimental investigations on all aspects of the respiratory system in health and disease. Clinical improvements in the diagnosis and treatment of chest and lung diseases are covered, as are the latest findings in physiology, biochemistry, pathology, immunology and pharmacology. The journal includes classic features such as editorials that accompany original articles in clinical and basic science research, reviews and letters to the editor. Further sections are: Technical Notes, The Eye Catcher, What’s Your Diagnosis?, The Opinion Corner, New Drugs in Respiratory Medicine, New Insights from Clinical Practice and Guidelines. ''Respiration'' is the official journal of the Swiss Society for Pneumology (SGP) and also home to the European Association for Bronchology and Interventional Pulmonology (EABIP), which occupies a dedicated section on Interventional Pulmonology in the journal. This modern mix of different features and a stringent peer-review process by a dedicated editorial board make ''Respiration'' a complete guide to progress in thoracic medicine.