对接受加速肾上腺素胶原交联的患者进行6个月的随访。

Alina-Cristina Chiraples, Diana Maria Darabus, Horia Tudor Stanca, Mihnea Munteanu
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引用次数: 0

摘要

目的:加速胶原交联(Accelerated Collagen交联,简称A-CXL)以其高效、快速的特点被广泛应用于圆锥角膜的治疗。本文旨在确定治疗前和治疗后六个月视力参数和地形测量的相关变化。方法:回顾性分析2021年5月至2023年6月期间接受A- cxl手术的20例患者的30只眼,随访至少6个月。术前、术后6个月比较未矫正视力、最佳矫正视力、球形、圆柱形屈光度及Kmax、SIf、SIb、KVf、KVb、BCVf、BCVb、TCT、CCT等地形图测量值。结果:加速胶原交联(A-CXL)后,BCVA改善,眼柱屈光度和Kmax值降低,角膜中央厚度(CCT)和最薄角膜厚度(TCT)升高。讨论:本研究在分组研究的异质性、测量角膜中心厚度和最薄角膜厚度的良好结果、屈光度和视力的良好演变等方面与其他研究结果相当。具体地形指标SIf/SIb、KVf/KVb、BCVf/BCVb、Kmax在随访6个月时差异不大,认为无统计学意义。其他研究表明,1年检查的相关性更好,6个月随访的结果也类似。结论:该方法的主要优点是持续时间短,干扰最小,视力得到改善,可再次介入治疗,效果较好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A 6-month follow-up for patients who underwent Accelerated Epi-on Collagen Crosslinking.

Purpose: Accelerated Collagen Crosslinking (A-CXL) is widely used worldwide as an effective treatment for keratoconus due to its efficiency and rapidity. This paper aims to identify relevant changes in visual acuity parameters and topographic measurements before and six months after treatment.

Methods: A total of 30 eyes from 20 patients who underwent A-CXL between May 2021 and June 2023 and had at least six months of follow-up were analyzed retrospectively. Comparisons between uncorrected visual acuity, best corrected visual acuity, spherical and cylinder diopters, and topographic measurements like Kmax, SIf, SIb, KVf, KVb, BCVf, BCVb, TCT, and CCT were made before and six months after surgery.

Results: After the accelerated Collagen crosslinking (A-CXL), BCVA improved, cylinder diopters and Kmax values were reduced, and central corneal thickness (CCT) and thinnest corneal thickness (TCT) were elevated.

Discussion: The study has shown results comparable with other studies regarding the heterogeneity of the group study, good outcomes in measuring the corneal central thickness and thinnest corneal thickness, and good evolution of the refraction and visual acuity. Regarding the specific topography markers, like SIf/SIb, KVf/KVb, BCVf/BCVb, and Kmax, minor differences were observed at 6 months follow-up and were not considered statistically relevant. Other studies show a better correlation at 1-year check-ups and similar results at 6-month follow-ups.

Conclusion: This method's main benefits are its brief duration and minimum intrusion, improvement of visual acuity, and the possibility of reintervention for better outcomes.

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