用于潜在纳米药物开发的合成和天然缩醛原自组装纳米载体（Adv. therapy . 2/2025）

IF 3.7 4区医学 Q2 PHARMACOLOGY & PHARMACY

Advanced Therapeutics Pub Date : 2025-02-13 DOI:10.1002/adtp.202570004

Yu Wu, Borislav Angelov, Yuru Deng, Takehiko Fujino, Md Shamim Hossain, Thomas Bizien, Angelina Angelova

{"title":"用于潜在纳米药物开发的合成和天然缩醛原自组装纳米载体（Adv. therapy . 2/2025）","authors":"Yu Wu, Borislav Angelov, Yuru Deng, Takehiko Fujino, Md Shamim Hossain, Thomas Bizien, Angelina Angelova","doi":"10.1002/adtp.202570004","DOIUrl":null,"url":null,"abstract":"<p>In article 2400093, Angelina Angelova and co-workers use synchrotron small-angle X-ray scattering to reveal the variety of nanoassemblies (cubosomes, hexosomes, or vesicles) that scallop-derived plasmalogen phospholipids can form in mixtures with co-lipids. Plasmalogen-based nanotherapeutics exert anti-apoptotic effects and improve brain-derived neurotrophic factor (BDNF) protein expression required for neuronal cell survival.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":7284,"journal":{"name":"Advanced Therapeutics","volume":"8 2","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adtp.202570004","citationCount":"0","resultStr":"{\"title\":\"Self-Assembled Nanocarriers of Synthetic and Natural Plasmalogens for Potential Nanomedicine Development (Adv. Therap. 2/2025)\",\"authors\":\"Yu Wu, Borislav Angelov, Yuru Deng, Takehiko Fujino, Md Shamim Hossain, Thomas Bizien, Angelina Angelova\",\"doi\":\"10.1002/adtp.202570004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>In article 2400093, Angelina Angelova and co-workers use synchrotron small-angle X-ray scattering to reveal the variety of nanoassemblies (cubosomes, hexosomes, or vesicles) that scallop-derived plasmalogen phospholipids can form in mixtures with co-lipids. Plasmalogen-based nanotherapeutics exert anti-apoptotic effects and improve brain-derived neurotrophic factor (BDNF) protein expression required for neuronal cell survival.\\n\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":7284,\"journal\":{\"name\":\"Advanced Therapeutics\",\"volume\":\"8 2\",\"pages\":\"\"},\"PeriodicalIF\":3.7000,\"publicationDate\":\"2025-02-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adtp.202570004\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advanced Therapeutics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/adtp.202570004\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Therapeutics","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/adtp.202570004","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}

引用次数: 0

摘要

在文章2400093中，Angelina Angelova及其同事使用同步加速器小角度x射线散射揭示了扇贝衍生的磷脂可以与共脂混合形成的各种纳米组装体（立方体、自旋体或囊泡）。基于等离子体原的纳米治疗药物具有抗凋亡作用并改善神经元细胞存活所需的脑源性神经营养因子（BDNF）蛋白表达。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Self-Assembled Nanocarriers of Synthetic and Natural Plasmalogens for Potential Nanomedicine Development (Adv. Therap. 2/2025)

查看原文本刊更多论文

Self-Assembled Nanocarriers of Synthetic and Natural Plasmalogens for Potential Nanomedicine Development (Adv. Therap. 2/2025)

In article 2400093, Angelina Angelova and co-workers use synchrotron small-angle X-ray scattering to reveal the variety of nanoassemblies (cubosomes, hexosomes, or vesicles) that scallop-derived plasmalogen phospholipids can form in mixtures with co-lipids. Plasmalogen-based nanotherapeutics exert anti-apoptotic effects and improve brain-derived neurotrophic factor (BDNF) protein expression required for neuronal cell survival.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Advanced Therapeutics Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science

CiteScore

7.10

自引率

2.20%

发文量

130