肥胖引起疼痛的研究趋势和热点：近20年的文献计量学分析

IF 2 Q3 NEUROSCIENCES

IBRO Neuroscience Reports Pub Date : 2025-02-10 DOI:10.1016/j.ibneur.2025.02.001

Lei Gao , Yazhou Wen , Kunlin Guo, Renqi Li, Mao Mao, Shanwu Feng, Xian Wang

{"title":"肥胖引起疼痛的研究趋势和热点：近20年的文献计量学分析","authors":"Lei Gao , Yazhou Wen , Kunlin Guo, Renqi Li, Mao Mao, Shanwu Feng, Xian Wang","doi":"10.1016/j.ibneur.2025.02.001","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Obesity can directly lead to allodynia, increase the incidence of chronic pain, and aggravate existing pain. However, the mechanisms underlying obesity-related or obesity-induced pain are still not understood. Herein, we performed a comprehensive bibliometric analysis of obesity-related or obesity-induced pain, aiming to analyze the current trends and hot spots as well as explore the underlying mechanisms.</div></div><div><h3>Methods</h3><div>We searched reviews and articles on obesity-related or obesity-induced pain from 2005 to 2024 via the Web of Science Core Collection (WoSCC) database. We subsequently conducted bibliometric analysis employing WPS Office, a web-based bibliometric analysis platform (<span><span>https://bibliometric.com</span><svg><path></path></svg></span>), VOSviewer, Pajek, and CiteSpace.</div></div><div><h3>Results</h3><div>In total, 347 papers were identified for bibliometric analysis. The country, institution, and journal with the greatest influence were the USA, Albert Einstein College of Medicine, and Headache, respectively. Dr. Lipton RB and Dr. Karppinen J were the top 2 influential authors on the basis of their significant number of publications and citations. The keywords for the latest burst were \"inflammation,\" \"risk,\" \"neuropathic pain,\" \"gene-related peptide,\" \"knee osteoarthritis,\" and \"validation.\" Notably, the article titled \"The association between chronic obesity and pain\" by Okifuji A received the highest number of citations as well as the strongest citation burst. He and colleagues noted a significant correlation between obesity and pain in terms of clinical manifestations, but this connection is indirect and is modulated by certain biomechanical and structural alterations linked to obesity, inflammatory agents, mood disorders, sleep disturbances, and lifestyles.</div></div><div><h3>Conclusion</h3><div>There has been a notable surge in the number of articles published in the last two decades. The investigation into neuroendocrine and neuroimmune mechanisms underlying obesity-related or obesity-induced pain is expected to be a hot spot in the coming years. A potential strategy for treating chronic obesity and pain should pay attention to particular endocrine regulators, inflammatory cytokines, or immune cells that serve as central elements or crucial signaling pathways within this regulatory system.</div></div>","PeriodicalId":13195,"journal":{"name":"IBRO Neuroscience Reports","volume":"18 ","pages":"Pages 311-322"},"PeriodicalIF":2.0000,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Research trends and hot spots in obesity-induced pain: A bibliometric analysis of the last 20 years\",\"authors\":\"Lei Gao , Yazhou Wen , Kunlin Guo, Renqi Li, Mao Mao, Shanwu Feng, Xian Wang\",\"doi\":\"10.1016/j.ibneur.2025.02.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Obesity can directly lead to allodynia, increase the incidence of chronic pain, and aggravate existing pain. However, the mechanisms underlying obesity-related or obesity-induced pain are still not understood. Herein, we performed a comprehensive bibliometric analysis of obesity-related or obesity-induced pain, aiming to analyze the current trends and hot spots as well as explore the underlying mechanisms.</div></div><div><h3>Methods</h3><div>We searched reviews and articles on obesity-related or obesity-induced pain from 2005 to 2024 via the Web of Science Core Collection (WoSCC) database. We subsequently conducted bibliometric analysis employing WPS Office, a web-based bibliometric analysis platform (<span><span>https://bibliometric.com</span><svg><path></path></svg></span>), VOSviewer, Pajek, and CiteSpace.</div></div><div><h3>Results</h3><div>In total, 347 papers were identified for bibliometric analysis. The country, institution, and journal with the greatest influence were the USA, Albert Einstein College of Medicine, and Headache, respectively. Dr. Lipton RB and Dr. Karppinen J were the top 2 influential authors on the basis of their significant number of publications and citations. The keywords for the latest burst were \\\"inflammation,\\\" \\\"risk,\\\" \\\"neuropathic pain,\\\" \\\"gene-related peptide,\\\" \\\"knee osteoarthritis,\\\" and \\\"validation.\\\" Notably, the article titled \\\"The association between chronic obesity and pain\\\" by Okifuji A received the highest number of citations as well as the strongest citation burst. He and colleagues noted a significant correlation between obesity and pain in terms of clinical manifestations, but this connection is indirect and is modulated by certain biomechanical and structural alterations linked to obesity, inflammatory agents, mood disorders, sleep disturbances, and lifestyles.</div></div><div><h3>Conclusion</h3><div>There has been a notable surge in the number of articles published in the last two decades. The investigation into neuroendocrine and neuroimmune mechanisms underlying obesity-related or obesity-induced pain is expected to be a hot spot in the coming years. A potential strategy for treating chronic obesity and pain should pay attention to particular endocrine regulators, inflammatory cytokines, or immune cells that serve as central elements or crucial signaling pathways within this regulatory system.</div></div>\",\"PeriodicalId\":13195,\"journal\":{\"name\":\"IBRO Neuroscience Reports\",\"volume\":\"18 \",\"pages\":\"Pages 311-322\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2025-02-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IBRO Neuroscience Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2667242125000193\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IBRO Neuroscience Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2667242125000193","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NEUROSCIENCES","Score":null,"Total":0}

引用次数: 0

摘要

研究背景肥胖可直接导致异常性疼痛，增加慢性疼痛的发生率，加重现有疼痛。然而，肥胖相关或肥胖引起的疼痛的机制仍不清楚。在此，我们对肥胖相关或肥胖引起的疼痛进行了全面的文献计量分析，旨在分析当前的趋势和热点，并探讨其潜在机制。方法通过Web of Science Core Collection （WoSCC）数据库检索2005 - 2024年间与肥胖相关或肥胖引起的疼痛相关的综述和文章。随后，我们使用基于web的文献计量分析平台WPS Office （https://bibliometric.com）、VOSviewer、Pajek和CiteSpace进行了文献计量分析。结果共筛选出347篇论文进行文献计量学分析。影响最大的国家、机构和期刊分别是美国、爱因斯坦医学院和头痛。Dr. Lipton RB和Dr. Karppinen J因其大量的出版物和引用而成为最具影响力的两位作者。最新爆发的关键词是“炎症”、“风险”、“神经性疼痛”、“基因相关肽”、“膝关节骨关节炎”和“验证”。值得一提的是，Okifuji A发表的题为《慢性肥胖与疼痛的关系》的文章被引用次数最多，而且被引用次数最多。他和同事们注意到，就临床表现而言，肥胖和疼痛之间存在显著的相关性，但这种联系是间接的，并受到与肥胖、炎症因子、情绪障碍、睡眠障碍和生活方式有关的某些生物力学和结构改变的调节。在过去的二十年里，发表的文章数量有了显著的增长。对肥胖相关或肥胖引起的疼痛的神经内分泌和神经免疫机制的研究有望成为未来几年的热点。治疗慢性肥胖和疼痛的潜在策略应该关注特定的内分泌调节因子、炎症细胞因子或免疫细胞，它们在这个调节系统中充当中心元件或关键信号通路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Research trends and hot spots in obesity-induced pain: A bibliometric analysis of the last 20 years

Background

Obesity can directly lead to allodynia, increase the incidence of chronic pain, and aggravate existing pain. However, the mechanisms underlying obesity-related or obesity-induced pain are still not understood. Herein, we performed a comprehensive bibliometric analysis of obesity-related or obesity-induced pain, aiming to analyze the current trends and hot spots as well as explore the underlying mechanisms.

Methods

We searched reviews and articles on obesity-related or obesity-induced pain from 2005 to 2024 via the Web of Science Core Collection (WoSCC) database. We subsequently conducted bibliometric analysis employing WPS Office, a web-based bibliometric analysis platform (https://bibliometric.com), VOSviewer, Pajek, and CiteSpace.

Results

In total, 347 papers were identified for bibliometric analysis. The country, institution, and journal with the greatest influence were the USA, Albert Einstein College of Medicine, and Headache, respectively. Dr. Lipton RB and Dr. Karppinen J were the top 2 influential authors on the basis of their significant number of publications and citations. The keywords for the latest burst were "inflammation," "risk," "neuropathic pain," "gene-related peptide," "knee osteoarthritis," and "validation." Notably, the article titled "The association between chronic obesity and pain" by Okifuji A received the highest number of citations as well as the strongest citation burst. He and colleagues noted a significant correlation between obesity and pain in terms of clinical manifestations, but this connection is indirect and is modulated by certain biomechanical and structural alterations linked to obesity, inflammatory agents, mood disorders, sleep disturbances, and lifestyles.

Conclusion

There has been a notable surge in the number of articles published in the last two decades. The investigation into neuroendocrine and neuroimmune mechanisms underlying obesity-related or obesity-induced pain is expected to be a hot spot in the coming years. A potential strategy for treating chronic obesity and pain should pay attention to particular endocrine regulators, inflammatory cytokines, or immune cells that serve as central elements or crucial signaling pathways within this regulatory system.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊