用绿色溶剂作为超临界二氧化碳萃取的助溶剂：富含抗氧化剂和抗菌剂的萃取物的一个有前途的来源

IF 5.5 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Sustainable Chemistry and Pharmacy Pub Date : 2025-02-12 DOI:10.1016/j.scp.2025.101950

Hamza bouakline , Imane Ziani , Meryem Idrissi Yahyaoui , Francesco Corrias , Asehraou Abdeslam , Ali El Bachiri

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引用次数: 0

摘要

超临界CO2萃取及10%改性助溶剂混合CO2环保型提取黄连木鲜叶和干叶生物活性物质的研究。在150 bar， 45°C的条件下，以乙醇和水为共溶剂，支持超临界二氧化碳萃取（SFE-CO2）的极性，得到不同的黄连木叶片提取物。比较了纯CO2和改性剂CO2两种提取方法对新鲜和干燥黄豆叶的提取效率、化学成分、总酚类和总黄酮含量、抗氧化剂和抗菌活性的影响。结果表明，在提取率、化学成分、总多酚和总黄酮含量方面存在显著差异。与单纯的SFE-CO2萃取物相比，经水改性的SFE-CO2萃取物具有较强的抗氧化活性。相反，与共溶剂修饰的SFE-CO2萃取物相比，纯SFE-CO2萃取物具有重要的抗菌活性。

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Using green solvents as co-solvent in supercritical carbon dioxide extraction: A promising source of extracts rich in antioxidants and antimicrobials agents

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Using green solvents as co-solvent in supercritical carbon dioxide extraction: A promising source of extracts rich in antioxidants and antimicrobials agents

Investigation of supercritical CO₂ extraction and CO₂ mixture with "modified" co-solvent (10%) as an environmentally friendly technology for the extraction of bioactive compounds from fresh and dried leaves of Pistacia lentiscus. The different Pistacia lentiscus leaves extracts were obtained at 150 bar, 45 °C, the ethanol and water were utilized as co-solvents to support the polarity of supercritical carbon dioxide extraction (SFE-CO₂). The extraction efficiency, chemical compositions, total phenols and flavonoids content, antioxidants and antimicrobials activities have been compared using the both approach the pure CO₂ and modifier CO₂, for the fresh and dried Pistacia lentiscus leaves. As results, concerning the extraction yield, chemical composition, and total polyphenol and flavonoid content exhibited significant variations. As well as the SFE-CO₂ extracts modified by water showed important antioxidants activity compared to simple SFE-CO₂ extraction. In adverse the pure SFE-CO₂ extraction showed important antimicrobials activity compared to the SFE-CO₂ extracts modified by co-solvent.

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来源期刊

Sustainable Chemistry and Pharmacy Environmental Science-Pollution

CiteScore

8.20

自引率

6.70%

发文量

274

审稿时长

37 days

期刊介绍： Sustainable Chemistry and Pharmacy publishes research that is related to chemistry, pharmacy and sustainability science in a forward oriented manner. It provides a unique forum for the publication of innovative research on the intersection and overlap of chemistry and pharmacy on the one hand and sustainability on the other hand. This includes contributions related to increasing sustainability of chemistry and pharmaceutical science and industries itself as well as their products in relation to the contribution of these to sustainability itself. As an interdisciplinary and transdisciplinary journal it addresses all sustainability related issues along the life cycle of chemical and pharmaceutical products form resource related topics until the end of life of products. This includes not only natural science based approaches and issues but also from humanities, social science and economics as far as they are dealing with sustainability related to chemistry and pharmacy. Sustainable Chemistry and Pharmacy aims at bridging between disciplines as well as developing and developed countries.