一种用于增强尿液中葡萄糖浓度检测的紧凑型二维光子晶体生物医学传感器。

IF 3.9 2区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES
Mahmoud M Hamed, Nazmi A Mohammed, Kareem A Badawi
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引用次数: 0

摘要

本研究介绍了一种二维光子晶体(PhC)生物传感器的设计、模拟和评估,用于利用折射率变化检测尿液中的葡萄糖浓度。该传感器表现出优异的性能,在0-15 mg/dl的葡萄糖水平范围内达到20040.30 nm/RIU的灵敏度,质量因子为10424.55,检测限低至8 × 10-10,超过了文献报道的基准。紧凑的尺寸为16.8 × 17.6 μ m2,与现代制造技术兼容,所提出的设计非常适合集成到便携式诊断设备中。综合比较分析强调了其优越的灵敏度、超高质量因子和紧凑的设计,使其成为葡萄糖检测技术的重大进步。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A Compact 2-D photonic crystal biomedical sensor for enhanced glucose concentration detection in urine.

A Compact 2-D photonic crystal biomedical sensor for enhanced glucose concentration detection in urine.

A Compact 2-D photonic crystal biomedical sensor for enhanced glucose concentration detection in urine.

A Compact 2-D photonic crystal biomedical sensor for enhanced glucose concentration detection in urine.

This study introduces a 2-D Photonic Crystal (PhC) biosensor designed, simulated, and evaluated for detecting glucose concentrations in urine by utilizing refractive index variations. The sensor demonstrates exceptional performance, achieving a sensitivity of 20,040.30 nm/RIU for glucose levels ranging from 0-15 mg/dl, a quality factor of 10,424.55, and a detection limit as low as 8 × 10-10, surpassing benchmarks reported in the literature. With compact dimensions of 16.8 × 17.6 µm2 and compatibility with modern fabrication techniques, the proposed design is well suited for integration into portable diagnostic devices. A comprehensive comparative analysis underscores its superior sensitivity, ultra-high quality factor, and compact design, establishing it as a major advancement in glucose detection technology.

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来源期刊
Scientific Reports
Scientific Reports Natural Science Disciplines-
CiteScore
7.50
自引率
4.30%
发文量
19567
审稿时长
3.9 months
期刊介绍: We publish original research from all areas of the natural sciences, psychology, medicine and engineering. You can learn more about what we publish by browsing our specific scientific subject areas below or explore Scientific Reports by browsing all articles and collections. Scientific Reports has a 2-year impact factor: 4.380 (2021), and is the 6th most-cited journal in the world, with more than 540,000 citations in 2020 (Clarivate Analytics, 2021). •Engineering Engineering covers all aspects of engineering, technology, and applied science. It plays a crucial role in the development of technologies to address some of the world''s biggest challenges, helping to save lives and improve the way we live. •Physical sciences Physical sciences are those academic disciplines that aim to uncover the underlying laws of nature — often written in the language of mathematics. It is a collective term for areas of study including astronomy, chemistry, materials science and physics. •Earth and environmental sciences Earth and environmental sciences cover all aspects of Earth and planetary science and broadly encompass solid Earth processes, surface and atmospheric dynamics, Earth system history, climate and climate change, marine and freshwater systems, and ecology. It also considers the interactions between humans and these systems. •Biological sciences Biological sciences encompass all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants. •Health sciences The health sciences study health, disease and healthcare. This field of study aims to develop knowledge, interventions and technology for use in healthcare to improve the treatment of patients.
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