A Corrado, G Scidà, J Abuqwider, E Annuzzi, A Giosuè, F Pisano, G Annuzzi, L Bozzetto
{"title":"先进技术使用者的睡眠质量、晚餐时间和血糖控制之间的相互作用：一项针对 1 型糖尿病成人的研究。","authors":"A Corrado, G Scidà, J Abuqwider, E Annuzzi, A Giosuè, F Pisano, G Annuzzi, L Bozzetto","doi":"10.1016/j.diabres.2025.112034","DOIUrl":null,"url":null,"abstract":"<p><strong>Aims: </strong>To explore the interplay among sleep quality, dinner timing, and glycemic control in adults with type 1 diabetes (T1D) using advanced diabetes technologies.</p><p><strong>Methods: </strong>T1D adults on automated (AID, n = 122) or non-automated (CSII, n = 67) insulin delivery systems completed the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Two-week CGM-metrics, HbA1c, and post-dinner glucose control were compared by independent T-test in Good vs. Bad-sleepers (PSQI-score above 5) or in Early vs. Late-eaters (above median of the cohort's dinner time).</p><p><strong>Results: </strong>Time-below-range (TBR)<sub>70-54</sub> (2.1 ± 2.0 vs. 1.3 ± 1.2 %), TBR<sub>54</sub> (0.7 ± 1.0 vs. 0.2 ± 0.4 %), and coefficient of variation (34.4 ± 5.3 vs. 31.8 ± 5.2 %) were significantly higher in Bad-sleepers than Good-sleepers (p < 0.05 for all). Late-eaters, particularly among AID users, showed higher HbA1c and lower TBR<sub>70-54</sub>, and, after dinner, higher TAR<sub>180-250</sub> and lower Time-in-range<sub>70-180</sub> than Early-eaters (p < 0.05 for all). At multiple regression analysis, dinner time was a main predictor of HbA1c, and TBR<sub>54</sub> a main predictor of sleep quality.</p><p><strong>Conclusions: </strong>The rate of hypoglycemia and dinner timing are key factors affecting both sleep quality and glycemic control in adults with T1D. Addressing lifestyle habits, including dinner timing and fear of hypoglycemia, may still be needed in users of AID.</p>","PeriodicalId":11249,"journal":{"name":"Diabetes research and clinical practice","volume":" ","pages":"112034"},"PeriodicalIF":6.1000,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Interplay among sleep quality, dinner timing, and blood glucose control in users of advanced technologies: A study in a cohort of adults with type 1 diabetes.\",\"authors\":\"A Corrado, G Scidà, J Abuqwider, E Annuzzi, A Giosuè, F Pisano, G Annuzzi, L Bozzetto\",\"doi\":\"10.1016/j.diabres.2025.112034\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aims: </strong>To explore the interplay among sleep quality, dinner timing, and glycemic control in adults with type 1 diabetes (T1D) using advanced diabetes technologies.</p><p><strong>Methods: </strong>T1D adults on automated (AID, n = 122) or non-automated (CSII, n = 67) insulin delivery systems completed the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Two-week CGM-metrics, HbA1c, and post-dinner glucose control were compared by independent T-test in Good vs. Bad-sleepers (PSQI-score above 5) or in Early vs. Late-eaters (above median of the cohort's dinner time).</p><p><strong>Results: </strong>Time-below-range (TBR)<sub>70-54</sub> (2.1 ± 2.0 vs. 1.3 ± 1.2 %), TBR<sub>54</sub> (0.7 ± 1.0 vs. 0.2 ± 0.4 %), and coefficient of variation (34.4 ± 5.3 vs. 31.8 ± 5.2 %) were significantly higher in Bad-sleepers than Good-sleepers (p < 0.05 for all). Late-eaters, particularly among AID users, showed higher HbA1c and lower TBR<sub>70-54</sub>, and, after dinner, higher TAR<sub>180-250</sub> and lower Time-in-range<sub>70-180</sub> than Early-eaters (p < 0.05 for all). At multiple regression analysis, dinner time was a main predictor of HbA1c, and TBR<sub>54</sub> a main predictor of sleep quality.</p><p><strong>Conclusions: </strong>The rate of hypoglycemia and dinner timing are key factors affecting both sleep quality and glycemic control in adults with T1D. Addressing lifestyle habits, including dinner timing and fear of hypoglycemia, may still be needed in users of AID.</p>\",\"PeriodicalId\":11249,\"journal\":{\"name\":\"Diabetes research and clinical practice\",\"volume\":\" \",\"pages\":\"112034\"},\"PeriodicalIF\":6.1000,\"publicationDate\":\"2025-02-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Diabetes research and clinical practice\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.diabres.2025.112034\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diabetes research and clinical practice","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.diabres.2025.112034","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
Interplay among sleep quality, dinner timing, and blood glucose control in users of advanced technologies: A study in a cohort of adults with type 1 diabetes.
Aims: To explore the interplay among sleep quality, dinner timing, and glycemic control in adults with type 1 diabetes (T1D) using advanced diabetes technologies.
Methods: T1D adults on automated (AID, n = 122) or non-automated (CSII, n = 67) insulin delivery systems completed the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Two-week CGM-metrics, HbA1c, and post-dinner glucose control were compared by independent T-test in Good vs. Bad-sleepers (PSQI-score above 5) or in Early vs. Late-eaters (above median of the cohort's dinner time).
Results: Time-below-range (TBR)70-54 (2.1 ± 2.0 vs. 1.3 ± 1.2 %), TBR54 (0.7 ± 1.0 vs. 0.2 ± 0.4 %), and coefficient of variation (34.4 ± 5.3 vs. 31.8 ± 5.2 %) were significantly higher in Bad-sleepers than Good-sleepers (p < 0.05 for all). Late-eaters, particularly among AID users, showed higher HbA1c and lower TBR70-54, and, after dinner, higher TAR180-250 and lower Time-in-range70-180 than Early-eaters (p < 0.05 for all). At multiple regression analysis, dinner time was a main predictor of HbA1c, and TBR54 a main predictor of sleep quality.
Conclusions: The rate of hypoglycemia and dinner timing are key factors affecting both sleep quality and glycemic control in adults with T1D. Addressing lifestyle habits, including dinner timing and fear of hypoglycemia, may still be needed in users of AID.
期刊介绍：
Diabetes Research and Clinical Practice is an international journal for health-care providers and clinically oriented researchers that publishes high-quality original research articles and expert reviews in diabetes and related areas. The role of the journal is to provide a venue for dissemination of knowledge and discussion of topics related to diabetes clinical research and patient care. Topics of focus include translational science, genetics, immunology, nutrition, psychosocial research, epidemiology, prevention, socio-economic research, complications, new treatments, technologies and therapy.
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