扩散混合条件下共轭二烯、CH酸和甲醛的三组分反应。

IF 2.2 4区化学 Q2 CHEMISTRY, ORGANIC

Beilstein Journal of Organic Chemistry Pub Date : 2025-02-04 eCollection Date: 2025-01-01 DOI:10.3762/bjoc.21.18

Dmitry E Shybanov, Maxim E Kukushkin, Eugene V Babaev, Nikolai V Zyk, Elena K Beloglazkina

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引用次数: 0

摘要

在没有强酸和强碱的情况下，利用挥发性试剂的扩散混合技术，在室温下成功地合成了活性亚甲基化合物和甲醛的crotonic缩合物。所形成的加合物是高活性中间体，能够在三组分反应中与二烯反应，从而形成Diels-Alder主反应产物。

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Three-component reactions of conjugated dienes, CH acids and formaldehyde under diffusion mixing conditions.

A diffusion mixing technique with a volatile reagent was successfully used to generate crotonic condensation adducts of active methylene compounds and formaldehyde at room temperature in the absence of strong acids and bases. The formed adducts were highly reactive intermediates capable of reacting with dienes in a three-component reaction, leading to the formation of Diels-Alder main reaction products.

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来源期刊

Beilstein Journal of Organic Chemistry 化学-有机化学

CiteScore

4.90

自引率

3.70%

发文量

167

审稿时长

1.4 months

期刊介绍： The Beilstein Journal of Organic Chemistry is an international, peer-reviewed, Open Access journal. It provides a unique platform for rapid publication without any charges (free for author and reader) – Platinum Open Access. The content is freely accessible 365 days a year to any user worldwide. Articles are available online immediately upon publication and are publicly archived in all major repositories. In addition, it provides a platform for publishing thematic issues (theme-based collections of articles) on topical issues in organic chemistry. The journal publishes high quality research and reviews in all areas of organic chemistry, including organic synthesis, organic reactions, natural product chemistry, structural investigations, supramolecular chemistry and chemical biology.