沉积海洋细菌CGMCC 1.7287T:一种从海洋沉积物中分离的聚羟基烷酸盐生产细菌的基因组研究

IF 1.3 4区 生物学 Q4 GENETICS & HEREDITY
Meng-Ru Wang, Yuke Zhang, Zheng-Jun Li
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引用次数: 0

摘要

聚羟基烷酸酯(PHA)是一种具有生物可降解性、生物相容性和生物可再生性等优良性能的聚酯材料。沉积海洋细菌CGMCC 1.7287T从东海海洋沉积物中分离得到,能够以挥发性脂肪酸为底物生产PHA。本文报道了M. sediminicola CGMCC 1.7287T的基因组特征,该染色体长3554135 bp, GC含量为56.10%。基因注释分析显示,该细菌含有参与挥发性脂肪酸利用、PHA合成和外托碱积累的酶。外托因合成相关基因的存在表明,该细菌具有抗逆性和细胞保护机制,以适应盐水环境。这些基因组特征为进一步开展海洋细菌基因工程,有效利用挥发性脂肪酸生产PHA和通过外托氨酸积累增强胁迫耐受性提供了重要参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Genomic insights into Marinobacterium sediminicola CGMCC 1.7287T: A polyhydroxyalkanoate-producing bacterium isolated from marine sediment
Polyhydroxyalkanoate (PHA) is a promising polyester with superior properties including biodegradability, biocompatibility, and biorenewability. Marinobacterium sediminicola CGMCC 1.7287T, isolated from marine sediment in the East China Sea, has been found capable of producing PHA using volatile fatty acids as cost-effective substrates. Here, we report the genomic characteristics of M. sediminicola CGMCC 1.7287T, which possesses a circular chromosome of 3,554,135 bp with a GC content of 56.10 %. Gene annotation analysis revealed that the bacterium harbors enzymes involved in volatile fatty acids utilization, PHA synthesis, and ectoine accumulation. The presence of genes associated with ectoine synthesis suggests that this bacterium has stress resistance and cellular protection mechanism to adapt to saline environments. The genomic features provide important references for further genetic engineering of marine bacteria to effectively utilize volatile fatty acids for PHA production and enhance stress tolerance through ectoine accumulation.
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来源期刊
Marine genomics
Marine genomics 生物-遗传学
CiteScore
3.60
自引率
5.30%
发文量
50
审稿时长
29 days
期刊介绍: The journal publishes papers on all functional and evolutionary aspects of genes, chromatin, chromosomes and (meta)genomes of marine (and freshwater) organisms. It deals with new genome-enabled insights into the broader framework of environmental science. Topics within the scope of this journal include: • Population genomics and ecology • Evolutionary and developmental genomics • Comparative genomics • Metagenomics • Environmental genomics • Systems biology More specific topics include: geographic and phylogenomic characterization of aquatic organisms, metabolic capacities and pathways of organisms and communities, biogeochemical cycles, genomics and integrative approaches applied to microbial ecology including (meta)transcriptomics and (meta)proteomics, tracking of infectious diseases, environmental stress, global climate change and ecosystem modelling.
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