Camran R Nezhat, Tomiko T Oskotsky, Joshua F Robinson, Susan J Fisher, Angie Tsuei, Binya Liu, Juan C Irwin, Brice Gaudilliere, Marina Sirota, David K Stevenson, Linda C Giudice
{"title":"通过手术、组学、健康数据和人工智能研究子宫内膜异位症表型的现实世界视角。","authors":"Camran R Nezhat, Tomiko T Oskotsky, Joshua F Robinson, Susan J Fisher, Angie Tsuei, Binya Liu, Juan C Irwin, Brice Gaudilliere, Marina Sirota, David K Stevenson, Linda C Giudice","doi":"10.1038/s44294-024-00052-w","DOIUrl":null,"url":null,"abstract":"<p><p>Endometriosis is an enigmatic disease whose diagnosis and management are being transformed through innovative surgical, molecular, and computational technologies. Integrating single-cell and other omic disease data with clinical and surgical metadata can identify multiple disease subtypes with translation to novel diagnostics and therapeutics. Herein, we present real-world perspectives on endometriosis and the importance of multidisciplinary collaboration in informing molecular, epidemiologic, and cell-specific data in the clinical and surgical contexts.</p>","PeriodicalId":520241,"journal":{"name":"npj women's health","volume":"3 1","pages":"8"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11802455/pdf/","citationCount":"0","resultStr":"{\"title\":\"Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence.\",\"authors\":\"Camran R Nezhat, Tomiko T Oskotsky, Joshua F Robinson, Susan J Fisher, Angie Tsuei, Binya Liu, Juan C Irwin, Brice Gaudilliere, Marina Sirota, David K Stevenson, Linda C Giudice\",\"doi\":\"10.1038/s44294-024-00052-w\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Endometriosis is an enigmatic disease whose diagnosis and management are being transformed through innovative surgical, molecular, and computational technologies. Integrating single-cell and other omic disease data with clinical and surgical metadata can identify multiple disease subtypes with translation to novel diagnostics and therapeutics. Herein, we present real-world perspectives on endometriosis and the importance of multidisciplinary collaboration in informing molecular, epidemiologic, and cell-specific data in the clinical and surgical contexts.</p>\",\"PeriodicalId\":520241,\"journal\":{\"name\":\"npj women's health\",\"volume\":\"3 1\",\"pages\":\"8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11802455/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"npj women's health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1038/s44294-024-00052-w\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/2/6 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"npj women's health","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1038/s44294-024-00052-w","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/6 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence.
Endometriosis is an enigmatic disease whose diagnosis and management are being transformed through innovative surgical, molecular, and computational technologies. Integrating single-cell and other omic disease data with clinical and surgical metadata can identify multiple disease subtypes with translation to novel diagnostics and therapeutics. Herein, we present real-world perspectives on endometriosis and the importance of multidisciplinary collaboration in informing molecular, epidemiologic, and cell-specific data in the clinical and surgical contexts.