{"title":"儿童上睑下垂手术引起的角膜地形图改变。","authors":"Jun Shindo, Nozomi Matsumura, Jutaro Nakamura, Mizuki Asano, Tomoko Ohno, Nobuhisa Mizuki","doi":"10.2147/OPTH.S503661","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate changes in corneal morphology following pediatric lower-lid epiblepharon surgery using a topographic modeling system 5 (TMS-5<sup>®</sup>).</p><p><strong>Patients and methods: </strong>A randomized controlled trial compared two surgical interventions for pediatric epiblepharon: incisional (modified Hotz procedure with lid margin splitting) and nonincisional. Corneal topography analysis using the TMS-5<sup>®</sup> served as an outcome measure. The study included 89 eyes from 50 children aged 3-12 years (mean age, 7.5 ± 2.4 years) diagnosed with moderate epiblepharon. Patients were randomly assigned to the incisional (45 eyes from 25 patients) or nonincisional (44 eyes from 25 patients) groups. Parameters including surface regularity index (SRI), Standard Deviation of Corneal Power (SDP), Irregular Astigmatism Index (IAI), and corneal astigmatism (CYL) were evaluated. The positive rate of Keratoconus Screening System (Keratoconus Index [KCI] and Keratoconus Severity Index [KSI]) was assessed.</p><p><strong>Results: </strong>The 6-month postoperative mean changes in corneal astigmatism were -0.34 ± 0.96 D (p = 0.012) and -0.21 ± 0.67 D (p = 0.22) in the incisional and nonincisional groups, respectively. Corneal astigmatism parameters significantly improved following both surgical procedures (p < 0.01). Preoperatively, 14.6% and 28.1% of patients were suspected of keratoconus using KCI and KSI, respectively, with a significantly reduced postoperative suspicion positivity rate (p < 0.01).</p><p><strong>Conclusion: </strong>Corneal astigmatism significantly improved in the incisional group. Both surgical methods improved the postoperative corneal surface smoothness, corneal refractive power variability, and irregular astigmatism. Patients with epiblepharon were occasionally suspected of keratoconus when assessed with TMS, with a higher frequency indicated by KSI.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"349-356"},"PeriodicalIF":0.0000,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11806347/pdf/","citationCount":"0","resultStr":"{\"title\":\"Corneal Topographic Changes Due to Pediatric Epiblepharon Surgery.\",\"authors\":\"Jun Shindo, Nozomi Matsumura, Jutaro Nakamura, Mizuki Asano, Tomoko Ohno, Nobuhisa Mizuki\",\"doi\":\"10.2147/OPTH.S503661\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>This study aimed to investigate changes in corneal morphology following pediatric lower-lid epiblepharon surgery using a topographic modeling system 5 (TMS-5<sup>®</sup>).</p><p><strong>Patients and methods: </strong>A randomized controlled trial compared two surgical interventions for pediatric epiblepharon: incisional (modified Hotz procedure with lid margin splitting) and nonincisional. Corneal topography analysis using the TMS-5<sup>®</sup> served as an outcome measure. The study included 89 eyes from 50 children aged 3-12 years (mean age, 7.5 ± 2.4 years) diagnosed with moderate epiblepharon. Patients were randomly assigned to the incisional (45 eyes from 25 patients) or nonincisional (44 eyes from 25 patients) groups. Parameters including surface regularity index (SRI), Standard Deviation of Corneal Power (SDP), Irregular Astigmatism Index (IAI), and corneal astigmatism (CYL) were evaluated. The positive rate of Keratoconus Screening System (Keratoconus Index [KCI] and Keratoconus Severity Index [KSI]) was assessed.</p><p><strong>Results: </strong>The 6-month postoperative mean changes in corneal astigmatism were -0.34 ± 0.96 D (p = 0.012) and -0.21 ± 0.67 D (p = 0.22) in the incisional and nonincisional groups, respectively. Corneal astigmatism parameters significantly improved following both surgical procedures (p < 0.01). Preoperatively, 14.6% and 28.1% of patients were suspected of keratoconus using KCI and KSI, respectively, with a significantly reduced postoperative suspicion positivity rate (p < 0.01).</p><p><strong>Conclusion: </strong>Corneal astigmatism significantly improved in the incisional group. Both surgical methods improved the postoperative corneal surface smoothness, corneal refractive power variability, and irregular astigmatism. Patients with epiblepharon were occasionally suspected of keratoconus when assessed with TMS, with a higher frequency indicated by KSI.</p>\",\"PeriodicalId\":93945,\"journal\":{\"name\":\"Clinical ophthalmology (Auckland, N.Z.)\",\"volume\":\"19 \",\"pages\":\"349-356\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-02-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11806347/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical ophthalmology (Auckland, N.Z.)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2147/OPTH.S503661\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical ophthalmology (Auckland, N.Z.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2147/OPTH.S503661","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的:本研究旨在利用地形建模系统5 (TMS-5®)研究儿童下眼睑外睑手术后角膜形态学的变化。患者和方法:一项随机对照试验比较了两种手术干预:切口(改良的Hotz手术加眼睑边缘分裂)和非切口。使用TMS-5®进行角膜地形图分析作为结果测量。该研究纳入了50例3-12岁(平均年龄7.5±2.4岁)诊断为中度上睑下垂的儿童的89只眼睛。患者随机分为切口组(25例患者45只眼)和非切口组(25例患者44只眼)。评估角膜表面规则指数(SRI)、角膜度数标准差(SDP)、不规则散光指数(IAI)、角膜散光(CYL)等参数。评估圆锥角膜筛查系统(角膜指数[KCI]和圆锥角膜严重程度指数[KSI])的阳性率。结果:切口组和非切口组术后6个月角膜散光平均变化分别为-0.34±0.96 D (p = 0.012)和-0.21±0.67 D (p = 0.22)。两种手术后角膜散光参数均显著改善(p < 0.01)。术前KCI和KSI分别有14.6%和28.1%的患者怀疑为圆锥角膜,术后怀疑阳性率显著降低(p < 0.01)。结论:切口组角膜散光明显改善。两种手术方法均可改善术后角膜表面平滑度、角膜屈光度变异性和不规则散光。外睑下垂患者在TMS评估时偶尔被怀疑为圆锥角膜,KSI显示的频率更高。
Corneal Topographic Changes Due to Pediatric Epiblepharon Surgery.
Purpose: This study aimed to investigate changes in corneal morphology following pediatric lower-lid epiblepharon surgery using a topographic modeling system 5 (TMS-5®).
Patients and methods: A randomized controlled trial compared two surgical interventions for pediatric epiblepharon: incisional (modified Hotz procedure with lid margin splitting) and nonincisional. Corneal topography analysis using the TMS-5® served as an outcome measure. The study included 89 eyes from 50 children aged 3-12 years (mean age, 7.5 ± 2.4 years) diagnosed with moderate epiblepharon. Patients were randomly assigned to the incisional (45 eyes from 25 patients) or nonincisional (44 eyes from 25 patients) groups. Parameters including surface regularity index (SRI), Standard Deviation of Corneal Power (SDP), Irregular Astigmatism Index (IAI), and corneal astigmatism (CYL) were evaluated. The positive rate of Keratoconus Screening System (Keratoconus Index [KCI] and Keratoconus Severity Index [KSI]) was assessed.
Results: The 6-month postoperative mean changes in corneal astigmatism were -0.34 ± 0.96 D (p = 0.012) and -0.21 ± 0.67 D (p = 0.22) in the incisional and nonincisional groups, respectively. Corneal astigmatism parameters significantly improved following both surgical procedures (p < 0.01). Preoperatively, 14.6% and 28.1% of patients were suspected of keratoconus using KCI and KSI, respectively, with a significantly reduced postoperative suspicion positivity rate (p < 0.01).
Conclusion: Corneal astigmatism significantly improved in the incisional group. Both surgical methods improved the postoperative corneal surface smoothness, corneal refractive power variability, and irregular astigmatism. Patients with epiblepharon were occasionally suspected of keratoconus when assessed with TMS, with a higher frequency indicated by KSI.