与人类6型疱疹病毒相关的视网膜炎:一例脾切除术患者的病例研究

IF 2.9 Q1 OPHTHALMOLOGY
Joana Santos-Oliveira, Ana Maria Cunha, Ana Filipa Moleiro, Margarida Ribeiro, Sónia Torres-Costa, Cláudia Oliveira-Ferreira, Ana Catarina Pedrosa, Joana Araújo, Luís Figueira, Marta Silva
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引用次数: 0

摘要

人类疱疹病毒-6 (HHV-6)是HHV家族的一员,是传染性葡萄膜炎的罕见病因。我们报告一例脾切除术患者,因侵袭性肺炎球菌疾病住院,诊断为右眼视网膜炎,视力良好(0.1 LogMAR)。考虑到脑脊液和血清中存在HHV-6聚合酶链反应(PCR),并伴有严重的中枢神经系统感染,这些眼科特征归因于HHV-6感染。局部应用皮质类固醇滴眼液、环戊酸酯和醋酸泼尼松龙软膏,全身静脉滴注更昔洛韦5mg /kg,连续14天,然后口服缬更昔洛韦900 mg,连续4周。诊断是迅速推定,使早期开始适当的治疗,并有助于保存良好的视力最初观察到。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Retinitis linked to human herpesvirus type 6: a case study in a splenectomised patient.

Human herpesvirus-6 (HHV-6) is a member of the HHV family and is a rare cause of infectious uveitis. We report a case of a splenectomised patient, hospitalised due to invasive pneumococcal disease, who was diagnosed with retinitis in the right eye, with good visual acuity (0.1 LogMAR). Given the presence of HHV-6 Polymerase chain reaction (PCR) in the cerebrospinal fluid and the serum and the coexistence of a severe central nervous system infection, the ophthalmological features were attributed to the HHV-6 infection. He was treated with topical corticosteroid eyedrops, cyclopentolate, and prednisolone acetate ointment and systemically with intravenous ganciclovir 5 mg/kg bid for 14 days and then oral valganciclovir 900 mg bid for 4 weeks. The diagnosis was promptly presumed, enabling the early initiation of appropriate treatment and contributing to the preservation of the good visual acuity initially observed.

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来源期刊
CiteScore
3.80
自引率
3.40%
发文量
39
审稿时长
13 weeks
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