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Capture of Totipotency in Mouse Embryonic Stem Cells in the Absence of Pdzk1 (Adv. Sci. 6/2025)
Capture of Totipotency
In article number 2408852, Ling Shuai, Qian Gao, Xiao-Ou Zhang, and co-workers report the generation of mouse totipotent-like stem cells through deletion of a single gene, Pdzk1. This novel and efficient strategy to acquire totipotency just like a beautiful genie has her powerful arrow to shoot the magic shining stars, representing the plasticity of development.
期刊介绍:
Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.