用于药物释放、传递和监测的便携式电化学试纸条

IF 6.1 Q1 CHEMISTRY, MULTIDISCIPLINARY
Sima Singh, Mohga Khater, Ada Raucci, Ovidio Catanzano, Fabiana Quaglia, Stefano Cinti
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引用次数: 0

摘要

在这里,我们引入了一个新的概念:一种可持续的、综合的数字医疗方法,利用便携式电化学条带来触发治疗物种释放并评估它们的发生。这是第一次,一种纳米化的、丝网印刷的条带电化学地触发金属离子的释放,与水凝胶结合将它们输送到目标部位,并使用相同的设备监测它们。为了证明这个新概念,铜离子被认为是一种可以在皮肤上传递和监测的模型物种。电分析、药物输送、小型化和材料科学的整合强调了个性化治疗中具有成本效益突破的潜力,为众多应用铺平了道路,并解决了当前传统技术的限制,如时间、复杂性和设备。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

All-in-One Portable Electrochemical Strips for Drug Release, Delivery and Monitoring

All-in-One Portable Electrochemical Strips for Drug Release, Delivery and Monitoring

Herein we introduce a novel concept: a sustainable, integrated approach to digital healthcare, utilizing a portable electrochemical strip to trigger therapeutic species release and assess their occurrence. For the first time, a nanomodified, screen-printed strip electrochemically triggers the release of metal ions, delivers them to the target site in combination with hydrogel and monitors them using the same device. To demonstrate the novel concept, copper ions have been considered a model species to be delivered and monitored on the skin. The integration of electroanalysis, drug delivery, miniaturization, and material science underscores the potential for a cost-effective breakthrough in personalized therapies, paving the way for numerous applications and addressing the current limitations of conventional technologies, such as time, complexity, and equipment.

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CiteScore
7.30
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