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IF 2.9 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Colorectal Disease Pub Date : 2025-02-09 DOI:10.1111/codi.70021

Anne Miles, Robert James Campbell Steele, Gemma Hutton, Stephen Morris

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引用次数: 0

摘要

目的直肠癌的治疗可能会给患者留下永久性的造口或肠功能障碍。在这项工作中，我们旨在研究直肠癌患者和非直肠癌患者对治疗结果的偏好。方法采用离散选择实验，对372例无造口、269例有造口和204例无造口的直肠癌患者进行了癌症复发风险、有无造口和肠功能障碍对治疗选择的影响。结果各组治疗偏好预测因子差异有统计学意义（p < 0.0001）。stoma-naïve组更重视避免造口，而功能优越组更重视避免肠功能障碍。降低复发风险在两组中被同等重视。结论有造口或肠功能障碍经历的患者对这些治疗结果的耐受性较高。听取生活在不同治疗结果中的患者的意见可以帮助新诊断的患者做好准备，并在患者有选择的情况下促进知情决策。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Preferences for treatment outcomes in rectal cancer: A discrete choice experiment among patients and healthy volunteers

查看原文本刊更多论文

Preferences for treatment outcomes in rectal cancer: A discrete choice experiment among patients and healthy volunteers

Aim

Treatment for rectal cancer can leave patients with a permanent stoma or bowel dysfunction. In this work we aimed to examine preferences for treatment outcomes among people with and without rectal cancer.

Method

Our discrete choice experiment examined the effect of risk of cancer recurrence, presence of a stoma and bowel dysfunction on treatment preferences in 372 rectal cancer patients without a stoma, 269 with a stoma and 204 people without cancer.

Results

Predictors of treatment preferences differed significantly between all groups (p < 0.0001). Avoiding a stoma was more important to stoma-naïve groups, while avoiding bowel dysfunction was more important to those with superior function. Reducing the risk of recurrence was valued highly, and equally, across the groups.

Conclusion

Experience of a stoma or bowel dysfunction resulted in higher tolerance of those treatment outcomes. Hearing from patients living with different treatment outcomes could help prepare newly diagnosed patients, and facilitate informed decision-making where patients have a choice.

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来源期刊

Colorectal Disease 医学-胃肠肝病学

CiteScore

6.10

自引率

11.80%

发文量

406

审稿时长

1.5 months

期刊介绍： Diseases of the colon and rectum are common and offer a number of exciting challenges. Clinical, diagnostic and basic science research is expanding rapidly. There is increasing demand from purchasers of health care and patients for clinicians to keep abreast of the latest research and developments, and to translate these into routine practice. Technological advances in diagnosis, surgical technique, new pharmaceuticals, molecular genetics and other basic sciences have transformed many aspects of how these diseases are managed. Such progress will accelerate. Colorectal Disease offers a real benefit to subscribers and authors. It is first and foremost a vehicle for publishing original research relating to the demanding, rapidly expanding field of colorectal diseases. Essential for surgeons, pathologists, oncologists, gastroenterologists and health professionals caring for patients with a disease of the lower GI tract, Colorectal Disease furthers education and inter-professional development by including regular review articles and discussions of current controversies. Note that the journal does not usually accept paediatric surgical papers.