子宫内膜样腺癌伴毛基质样分化：1例报告及文献复习

IF 1.2 Q3 OBSTETRICS & GYNECOLOGY

Gynecologic Oncology Reports Pub Date : 2025-02-01 DOI:10.1016/j.gore.2025.101693

L. Rusnell, Z. Al-Shamma, S.P. Bisch

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引用次数: 0

摘要

我们报告一例罕见的子宫毛基质样高级别子宫内膜样癌（PiMHEC）。我们对迄今为止报道的16例其他PiMHEC病例进行了全面的回顾，概述了我们的索引病例，并考虑了治疗方法，重点是分子分型。病例总结：这名44岁的患者在诊断时出现了广泛的转移性疾病，并通过联合放化疗初步临床改善。免疫治疗在临床过程中较晚开始，患者最终在诊断后6个月死于疾病。结论未来临床医生可根据PiMHEC病例报告制定治疗方案，并考虑早期开始免疫治疗。

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Uterine endometrioid adenocarcinoma with pilomatrix-like differentiation: A case report and review of the literature

Introduction

We present a rare case of uterine pilomatrix-like high grade endometrioid carcinoma (PiMHEC). We provide a thorough review of the 16 other PiMHEC cases reported to date, overview of our index case, and considerations for therapeutic approach with a focus on molecular subtyping.

Case Summary

This 44-year-old patient presented with widespread metastatic disease at time of diagnosis and initial clinical improvement with combination chemoradiotherapy. Immunotherapy was initiated later in the clinical course and the patient ultimately died of their disease 6 months post-diagnosis.

Conclusion

Future clinicians may utilize PiMHEC case reports to formulate a therapeutic regimen and consider early initiation of immunotherapy.

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来源期刊

Gynecologic Oncology Reports OBSTETRICS & GYNECOLOGY-

CiteScore

2.00

自引率

0.00%

发文量

183

审稿时长

41 days

期刊介绍： Gynecologic Oncology Reports is an online-only, open access journal devoted to the rapid publication of narrative review articles, survey articles, case reports, case series, letters to the editor regarding previously published manuscripts and other short communications in the field of gynecologic oncology. The journal will consider papers that concern tumors of the female reproductive tract, with originality, quality, and clarity the chief criteria of acceptance.