CRISPR-Cas技术用于病原体的快速检测

IF 11.8 1区化学 Q1 CHEMISTRY, ANALYTICAL

Trends in Analytical Chemistry Pub Date : 2025-02-04 DOI:10.1016/j.trac.2025.118174

Hossein Daneshgar , Moein Safarkhani , Soheil Sojdeh , Mojtaba Bagherzadeh , Navid Rabiee

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引用次数: 0

摘要

在与SARS-CoV-2、沙门氏菌和疟疾等全球病原体作斗争时，快速和精确的检测方法至关重要。传统方法往往面临成本和可及性的挑战，特别是在资源有限的地区。将CRISPR-Cas技术整合到检测过程中是一项改变游戏规则的技术，为即时使用提供了无与伦比的特异性和速度。这种方法符合绿色生物材料原则，强调生态友好性和资源效率。通过结合绿色生物材料，CRISPR-Cas系统变得更具可持续性、效率和环境敏感性。这种整合彻底改变了病原体检测，同时促进了环境管理。它不仅促进了快速检测，而且强调了对生态意识和诊断可持续性的承诺，为全球卫生带来了希望。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

CRISPR-Cas technology for rapid detection of pathogens

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CRISPR-Cas technology for rapid detection of pathogens

In battling global pathogens like SARS-CoV-2, salmonella, and malaria, rapid and precise detection methods are vital. Traditional approaches often face cost and accessibility challenges, especially in resource-limited areas. Integrating CRISPR-Cas technology into detection processes is a game-changer, offering unparalleled specificity and speed for point-of-care use. This method aligns with Green Biomaterials principles, emphasizing eco-friendliness and resource efficiency. By incorporating green biomaterials, the CRISPR-Cas system becomes more sustainable, efficient, and environmentally sensitive. This integration revolutionizes pathogen detection while promoting environmental stewardship. It not only advances rapid detection but also underscores a commitment to ecological consciousness and sustainability in diagnostics, offering promise for global health.

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来源期刊

Trends in Analytical Chemistry 化学-分析化学

CiteScore

20.00

自引率

4.60%

发文量

257

审稿时长

3.4 months

期刊介绍： TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.