Sandra Condori-Catachura, Sarah Ahannach, Monica Ticlla, Josiane Kenfack, Esemu Livo, Kingsley C Anukam, Viviana Pinedo-Cancino, Maria Carmen Collado, Maria Gloria Dominguez-Bello, Corrie Miller, Gabriel Vinderola, Sonja Merten, Gilbert G G Donders, Thies Gehrmann, Sarah Lebeer
{"title":"女性及其阴道微生物群的多样性。","authors":"Sandra Condori-Catachura, Sarah Ahannach, Monica Ticlla, Josiane Kenfack, Esemu Livo, Kingsley C Anukam, Viviana Pinedo-Cancino, Maria Carmen Collado, Maria Gloria Dominguez-Bello, Corrie Miller, Gabriel Vinderola, Sonja Merten, Gilbert G G Donders, Thies Gehrmann, Sarah Lebeer","doi":"10.1016/j.tim.2024.12.012","DOIUrl":null,"url":null,"abstract":"<p><p>Women's health is essential to global societal and economic wellbeing, yet health disparities remain prevalent. The vaginal microbiota plays a critical role in health, with research indicating that reduced levels of core bacteria, such as lactobacilli, are associated with conditions like bacterial vaginosis (BV) and increased infection susceptibility. Lower levels of vaginal lactobacilli are reported more frequently in women of African and Latin American descent compared with women of European and Asian descent. However, geographical and other study inclusion and analysis biases influence current research. This opinion highlights the need for a more comprehensive understanding of a 'healthy' vaginal microbiome. It underscores efforts to broaden global research on microbiome diversity in socially relevant contexts, avoiding inappropriate applications of terms such as race and ethnicity.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":" ","pages":""},"PeriodicalIF":14.0000,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Diversity in women and their vaginal microbiota.\",\"authors\":\"Sandra Condori-Catachura, Sarah Ahannach, Monica Ticlla, Josiane Kenfack, Esemu Livo, Kingsley C Anukam, Viviana Pinedo-Cancino, Maria Carmen Collado, Maria Gloria Dominguez-Bello, Corrie Miller, Gabriel Vinderola, Sonja Merten, Gilbert G G Donders, Thies Gehrmann, Sarah Lebeer\",\"doi\":\"10.1016/j.tim.2024.12.012\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Women's health is essential to global societal and economic wellbeing, yet health disparities remain prevalent. The vaginal microbiota plays a critical role in health, with research indicating that reduced levels of core bacteria, such as lactobacilli, are associated with conditions like bacterial vaginosis (BV) and increased infection susceptibility. Lower levels of vaginal lactobacilli are reported more frequently in women of African and Latin American descent compared with women of European and Asian descent. However, geographical and other study inclusion and analysis biases influence current research. This opinion highlights the need for a more comprehensive understanding of a 'healthy' vaginal microbiome. It underscores efforts to broaden global research on microbiome diversity in socially relevant contexts, avoiding inappropriate applications of terms such as race and ethnicity.</p>\",\"PeriodicalId\":23275,\"journal\":{\"name\":\"Trends in Microbiology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":14.0000,\"publicationDate\":\"2025-01-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Trends in Microbiology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1016/j.tim.2024.12.012\",\"RegionNum\":1,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Microbiology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.tim.2024.12.012","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Women's health is essential to global societal and economic wellbeing, yet health disparities remain prevalent. The vaginal microbiota plays a critical role in health, with research indicating that reduced levels of core bacteria, such as lactobacilli, are associated with conditions like bacterial vaginosis (BV) and increased infection susceptibility. Lower levels of vaginal lactobacilli are reported more frequently in women of African and Latin American descent compared with women of European and Asian descent. However, geographical and other study inclusion and analysis biases influence current research. This opinion highlights the need for a more comprehensive understanding of a 'healthy' vaginal microbiome. It underscores efforts to broaden global research on microbiome diversity in socially relevant contexts, avoiding inappropriate applications of terms such as race and ethnicity.
期刊介绍:
Trends in Microbiology serves as a comprehensive, multidisciplinary forum for discussing various aspects of microbiology, spanning cell biology, immunology, genetics, evolution, virology, bacteriology, protozoology, and mycology. In the rapidly evolving field of microbiology, technological advancements, especially in genome sequencing, impact prokaryote biology from pathogens to extremophiles, influencing developments in drugs, vaccines, and industrial enzyme research.