硫化氢缓解2型糖尿病患者血小板功能障碍。

IF 2.2 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Thrombosis and Thrombolysis Pub Date : 2025-03-01 Epub Date: 2025-02-07 DOI:10.1007/s11239-025-03071-9

Minqi Zhou, Difei Lu, Anna Jiang, Chenxu Zhao, Yao Lu, Bo Zheng, Linzi Miao, Youyuan Huang, Chenxue Qu, Ying Gao

引用次数: 0

摘要

高血糖通过降低血小板H2S浓度刺激血小板活化，可能导致心血管事件。外源性补充H2S可逆转高血糖状态下的异常血小板活化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Hydrogen sulphide alleviates platelet dysfunction in patients with type 2 diabetes.

Hyperglycaemia stimulate platelet activation by reducing platelet H₂S concentrations, potentially leading to cardiovascular events. Exogenous supplementation with H₂S reversed this abnormal platelet activation under hyperglycaemia.

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来源期刊

Journal of Thrombosis and Thrombolysis 医学-外周血管病

CiteScore

9.20

自引率

0.00%

发文量

112

审稿时长

4-8 weeks

期刊介绍： The Journal of Thrombosis and Thrombolysis is a long-awaited resource for contemporary cardiologists, hematologists, vascular medicine specialists and clinician-scientists actively involved in treatment decisions and clinical investigation of thrombotic disorders involving the cardiovascular and cerebrovascular systems. The principal focus of the Journal centers on the pathobiology of thrombosis and vascular disorders and the use of anticoagulants, platelet antagonists, cell-based therapies and interventions in scientific investigation, clinical-translational research and patient care. The Journal will publish original work which emphasizes the interface between fundamental scientific principles and clinical investigation, stimulating an interdisciplinary and scholarly dialogue in thrombosis and vascular science. Published works will also define platforms for translational research, drug development, clinical trials and patient-directed applications. The Journal of Thrombosis and Thrombolysis'' integrated format will expand the reader''s knowledge base and provide important insights for both the investigation and direct clinical application of the most rapidly growing fields in medicine-thrombosis and vascular science.