针刺治疗纤维肌痛后，压力痛阈值和疼痛感知影响对短期和长期疼痛减轻的差异预测。

IF 4.2 2区医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE

Journal of Integrative Medicine-Jim Pub Date : 2025-03-01 DOI:10.1016/j.joim.2025.01.005

Anne E Murphy , Anne Arewasikporn , Lisa Taylor-Swanson , David A Williams , Richard E Harris

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引用次数: 0

摘要

目的：针灸治疗纤维肌痛的疗效已得到证实；然而，这一人群的短期和长期镇痛反应的预测因素尚不清楚。方法：本文对一项单中心、盲法、假对照、随机纵向针灸治疗纤维肌痛的临床试验进行了二次分析。基线特征包括压痛阈值和疼痛干扰，而从基线到随访的疼痛强度的剩余变化是主要的结果测量。参与者被随机分为两组，一组接受verum （n = 36）或sham （n = 29）针灸治疗，为期12周（18次治疗），并从治疗开始进行了37周的随访。结果：基线压痛阈值较低的患者仅在治疗后立即接受假治疗，而压力痛阈值较高的患者在接受verum治疗后镇痛效果较好（B = -13.43, P = 0.001）。此外，无论治疗方式如何，基线疼痛的感知影响更大预示着更大的短期镇痛。压痛阈值不能预测长期治疗差异反应（B = -1.71, P = 0.66）。在基线疼痛感知影响和随后的长期镇痛之间，两组之间的关系有显著差异，与假手术组相比，那些感知到疼痛影响更大的患者在椎体针灸中表现出更好的长期镇痛效果（B = -11.37, P = 0.004）。结论：我们的研究结果支持使用自我报告的疼痛结果来预测针刺后纤维肌痛的长期镇痛。Murphy AE, Arewasikporn A, Taylor-Swanson L, Williams DA, Harris RE.针刺对纤维肌痛症患者短期和长期疼痛缓解的影响。集成医学[J]；打印前Epub。

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Pressure pain threshold and perceived impact of pain differentially predict short-term and long-term pain reduction following acupuncture in fibromyalgia

Objective

Acupuncture has demonstrated efficacy as a treatment for fibromyalgia; however, predictors of short- and long-term analgesic response in this population are not well understood.

Methods

This manuscript describes a secondary analysis of a single-center, blinded, sham-controlled, randomized longitudinal acupuncture clinical trial in fibromyalgia. Baseline characterization included pressure pain threshold and pain interference, while residualized change in pain intensity from baseline to follow-up served as the primary outcome measure. Participants were randomized into groups that received verum (n = 36) or sham (n = 29) acupuncture treatment over a 12-week period (18 treatments) and were followed for 37 weeks from the initiation of treatment.

Results

Lower pressure pain thresholds at baseline were associated with greater analgesia only in the sham treatment group immediately following treatment, while those with higher pressure pain thresholds had greater analgesia with verum treatment (B = –13.43, P = 0.001). Additionally, greater perceived impact of pain at baseline was predictive of greater short-term analgesia irrespective of treatment. Pressure pain threshold was not found to be predictive of long-term differential treatment response (B = –1.71, P = 0.66). There was a significant difference in the relationship between perceived impact of pain at baseline and subsequent long-term analgesia between groups where those with greater perceived impact of pain displayed improved long-term analgesia for verum acupuncture compared to the sham group (B = –11.37, P = 0.004).

Conclusion

Our results support the use of a self-reported pain outcome in predicting long-term analgesia following acupuncture in fibromyalgia.

Please cite this article as: Murphy AE, Arewasikporn A, Taylor-Swanson L, Williams DA, Harris RE. Pressure pain threshold and perceived impact of pain differentially predict short-term and long-term pain reduction following acupuncture in fibromyalgia. J Integr Med. 2025; 23(2): 152–158.

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来源期刊

Journal of Integrative Medicine-Jim Medicine-Complementary and Alternative Medicine

CiteScore

9.20

自引率

4.20%

发文量

3319

期刊介绍： The predecessor of JIM is the Journal of Chinese Integrative Medicine (Zhong Xi Yi Jie He Xue Bao). With this new, English-language publication, we are committed to make JIM an international platform for publishing high-quality papers on complementary and alternative medicine (CAM) and an open forum in which the different professions and international scholarly communities can exchange views, share research and their clinical experience, discuss CAM education, and confer about issues and problems in our various disciplines and in CAM as a whole in order to promote integrative medicine. JIM is indexed/abstracted in: MEDLINE/PubMed, ScienceDirect, Emerging Sources Citation Index (ESCI), Scopus, Embase, Chemical Abstracts (CA), CAB Abstracts, EBSCO, WPRIM, JST China, Chinese Science Citation Database (CSCD), and China National Knowledge Infrastructure (CNKI). JIM Editorial Office uses ThomsonReuters ScholarOne Manuscripts as submitting and review system (submission link: http://mc03.manuscriptcentral.com/jcim-en). JIM is published bimonthly. Manuscripts submitted to JIM should be written in English. Article types include but are not limited to randomized controlled and pragmatic trials, translational and patient-centered effectiveness outcome studies, case series and reports, clinical trial protocols, preclinical and basic science studies, systematic reviews and meta-analyses, papers on methodology and CAM history or education, conference proceedings, editorials, commentaries, short communications, book reviews, and letters to the editor. Our purpose is to publish a prestigious international journal for studies in integrative medicine. To achieve this aim, we seek to publish high-quality papers on any aspects of integrative medicine, such as acupuncture and traditional Chinese medicine, Ayurveda medicine, herbal medicine, homeopathy, nutrition, chiropractic, mind-body medicine, taichi, qigong, meditation, and any other modalities of CAM; our commitment to international scope ensures that research and progress from all regions of the world are widely covered. These ensure that articles published in JIM have the maximum exposure to the international scholarly community. JIM can help its authors let their papers reach the widest possible range of readers, and let all those who share an interest in their research field be concerned with their study.