超临界CO2辅助萃取，纯化和模拟从粗混合物游离脂肪酸-一个案例研究的油脂水解

IF 3.4 3区工程技术 Q2 CHEMISTRY, PHYSICAL

Journal of Supercritical Fluids Pub Date : 2025-02-04 DOI:10.1016/j.supflu.2025.106542

EK Anagha , R. Sariga , K. ShyamSundar , Rames C. Panda , M. Helen Kalavathy , S.N. Naik

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引用次数: 0

摘要

油脂是皮革工业的副产品，广泛应用于制药和油脂化学领域，作为甘油的来源/前体，通过水解塔在高压-温度下的水水解得到。虽然从底产物中提取甘油的标准程序已经建立，但从顶部粗混合物中纯化脂肪酸（FA）还需要注意。方法采用超临界流体萃取（SFE）对twitchell工艺中单个脂肪酸进行鉴定和分离。溶解度（Soave-Redlich-Kwong）和相图使用Matlab &；阿斯彭。用质谱法分析了产物的特性，结果表明：原料混合物中fa组分的比例为：4.3:32.2:43:0:20.4，其中C-14， C16, C16 = 2；与CH3OH溶剂相比，SFE溶剂对C18组分的提取效率更高。通过分析和表征发现，与标称提取方法相比，饱和FA的提取率提高了2-3倍，不饱和FA的提取率提高了9倍左右。离子液体（IL）与sfe溶剂的加入使其溶解度提高到92 %。建立了一个模型来验证研究结果。综上所述，SFE辅助IL提取的纯组分可用于进一步下游加工的油脂化学品的制备。

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Supercritical CO2 assisted extraction, purification and modelling of free fatty acids from the crude mixture – A case study of tallow hydrolysis

Background

Tallow, a by-product of the leather-industry, is widely used in pharmaceuticals and oleochemical applications as a source/precursor of glycerol, obtained by aqueous-hydrolysis under high-pressure-temperature from a hydrolyzing-tower. Though standard procedures of extracting glycerol from the bottom-product are well established, the purification of fatty-acids (FA) from the top crude-mixture needs attention

Method

This paper identifies and separates individual fatty-acids from the Twitchell-process using the supercritical-fluid-extraction (SFE). Solubilities (Soave-Redlich-Kwong) and phase-diagrams are obtained using Matlab & Aspen, respectively. The characteristics of the product are analyzed by mass-spectroscopy which reveals that the FA-components present in the crude-mixture in the ratio of 4.3:32.2:43.0:20.4 for C-14, C16, C16 = 2, and C18 components respectively are more efficiently extracted by the solvent of SFE compared to CH₃OH solvent

Findings

It has been found from the analysis and characterization that the rate of extraction is improved by 2–3 times in case of saturated while it’s about 9 times in-case-of unsaturated FA compared to the nominal method of extraction. Addition of ionic-liquid (IL) with SFE-solvent improved the solubility to 92 %. A model is formulated to validate the findings. It is suggested that the pure components extracted by SFE assisted by IL can be used for the preparation of oleochemicals in further downstream-processing.

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来源期刊

Journal of Supercritical Fluids 工程技术-工程：化工

CiteScore

7.60

自引率

10.30%

发文量

236

审稿时长

56 days

期刊介绍： The Journal of Supercritical Fluids is an international journal devoted to the fundamental and applied aspects of supercritical fluids and processes. Its aim is to provide a focused platform for academic and industrial researchers to report their findings and to have ready access to the advances in this rapidly growing field. Its coverage is multidisciplinary and includes both basic and applied topics. Thermodynamics and phase equilibria, reaction kinetics and rate processes, thermal and transport properties, and all topics related to processing such as separations (extraction, fractionation, purification, chromatography) nucleation and impregnation are within the scope. Accounts of specific engineering applications such as those encountered in food, fuel, natural products, minerals, pharmaceuticals and polymer industries are included. Topics related to high pressure equipment design, analytical techniques, sensors, and process control methodologies are also within the scope of the journal.