牛皮癣的神经免疫学：降钙素基因相关肽在其发病机制中的可能作用

IF 3.7 Q2 IMMUNOLOGY

Brain, behavior, & immunity - health Pub Date : 2025-01-30 DOI:10.1016/j.bbih.2025.100958

Joshua Kotlyar , Richard D. Granstein

{"title":"牛皮癣的神经免疫学：降钙素基因相关肽在其发病机制中的可能作用","authors":"Joshua Kotlyar , Richard D. Granstein","doi":"10.1016/j.bbih.2025.100958","DOIUrl":null,"url":null,"abstract":"<div><div>The nervous system has a complex interplay with the immune system, especially at barrier sites such as the skin. This allows it to play a role in a variety of cutaneous inflammatory disorders such as psoriasis, exerting effects on various immune cells via effector molecules such as neuropeptides. In this review, we discuss the role of calcitonin gene-related peptide in modulating the immune system and inflammation, with a focus on psoriasis.</div></div>","PeriodicalId":72454,"journal":{"name":"Brain, behavior, & immunity - health","volume":"44 ","pages":"Article 100958"},"PeriodicalIF":3.7000,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Neuroimmunology of psoriasis: Possible roles for calcitonin gene-related peptide in its pathogenesis\",\"authors\":\"Joshua Kotlyar , Richard D. Granstein\",\"doi\":\"10.1016/j.bbih.2025.100958\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The nervous system has a complex interplay with the immune system, especially at barrier sites such as the skin. This allows it to play a role in a variety of cutaneous inflammatory disorders such as psoriasis, exerting effects on various immune cells via effector molecules such as neuropeptides. In this review, we discuss the role of calcitonin gene-related peptide in modulating the immune system and inflammation, with a focus on psoriasis.</div></div>\",\"PeriodicalId\":72454,\"journal\":{\"name\":\"Brain, behavior, & immunity - health\",\"volume\":\"44 \",\"pages\":\"Article 100958\"},\"PeriodicalIF\":3.7000,\"publicationDate\":\"2025-01-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Brain, behavior, & immunity - health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S266635462500016X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"IMMUNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brain, behavior, & immunity - health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S266635462500016X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"IMMUNOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

神经系统与免疫系统有着复杂的相互作用，尤其是在皮肤等屏障部位。这使得它在多种皮肤炎症性疾病（如牛皮癣）中发挥作用，通过神经肽等效应分子对各种免疫细胞施加影响。在这篇综述中，我们讨论了降钙素基因相关肽在调节免疫系统和炎症中的作用，重点是银屑病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Neuroimmunology of psoriasis: Possible roles for calcitonin gene-related peptide in its pathogenesis

The nervous system has a complex interplay with the immune system, especially at barrier sites such as the skin. This allows it to play a role in a variety of cutaneous inflammatory disorders such as psoriasis, exerting effects on various immune cells via effector molecules such as neuropeptides. In this review, we discuss the role of calcitonin gene-related peptide in modulating the immune system and inflammation, with a focus on psoriasis.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Brain, behavior, & immunity - health Biological Psychiatry, Behavioral Neuroscience

CiteScore

8.50

自引率

0.00%

发文量

审稿时长

97 days