宫颈癌诊断的革命:从传统技术到生物传感器的转变

IF 10.61 Q3 Biochemistry, Genetics and Molecular Biology
Ubaid Mushtaq Naikoo , Roberto Pilloton , Humaira Farooqi , Jagriti Narang
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引用次数: 0

摘要

宫颈癌是全球女性患病和死亡的最重要原因,因此迫切需要有效的诊断工具。传统的诊断技术,如巴氏涂片检查和人乳头瘤病毒检测,虽然有效,但存在局限性,包括侵入性、敏感性可变和对临床基础设施的依赖。这篇综述探讨了生物传感器作为一种无创、经济、敏感的宫颈癌诊断替代方法的变革潜力。综合分析当前的生物传感器技术,强调其机制、优势和克服传统方法缺点的潜力。此外,本文还讨论了生物传感器设计的最新进展,包括集成纳米材料和护理点系统,这提高了它们的诊断准确性和可及性。在生物传感器的临床翻译的关键挑战也被解决,以及潜在的解决方案和未来的研究方向。通过强调从传统技术到生物传感器的转变,本综述强调了这些创新工具在改善宫颈癌早期检测和患者治疗结果方面的前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Revolutionizing cervical cancer diagnostics: A shift from traditional techniques to biosensors

Revolutionizing cervical cancer diagnostics: A shift from traditional techniques to biosensors
Cervical cancer is the most important contributor to ailment and death among females universally, highlighting the urgent need for effective diagnostic tools. Traditional diagnostic techniques, such as Pap smears and HPV testing, though effective, suffer from limitations including invasiveness, variable sensitivity, and dependence on clinical infrastructure. This review explores the transformative potential of biosensors as a non-invasive, cost-effective, and sensitive alternative for cervical cancer diagnostics. Comprehensive analysis of current biosensor technologies, emphasizing their mechanisms, advantages, and potential to overcome the drawbacks of conventional methods. Furthermore, the review discusses recent advancements in biosensor design, including integrating nanomaterials and point-of-care systems, which enhance their diagnostic accuracy and accessibility. Key challenges in the clinical translation of biosensors are also addressed, along with potential solutions and future research directions. By highlighting the shift from traditional techniques to biosensors, this review underscores the promise of these innovative tools in improving early detection and patient outcomes in cervical cancer care.
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来源期刊
Biosensors and Bioelectronics: X
Biosensors and Bioelectronics: X Biochemistry, Genetics and Molecular Biology-Biophysics
CiteScore
4.60
自引率
0.00%
发文量
166
审稿时长
54 days
期刊介绍: Biosensors and Bioelectronics: X, an open-access companion journal of Biosensors and Bioelectronics, boasts a 2020 Impact Factor of 10.61 (Journal Citation Reports, Clarivate Analytics 2021). Offering authors the opportunity to share their innovative work freely and globally, Biosensors and Bioelectronics: X aims to be a timely and permanent source of information. The journal publishes original research papers, review articles, communications, editorial highlights, perspectives, opinions, and commentaries at the intersection of technological advancements and high-impact applications. Manuscripts submitted to Biosensors and Bioelectronics: X are assessed based on originality and innovation in technology development or applications, aligning with the journal's goal to cater to a broad audience interested in this dynamic field.
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