高须动脉炎诊断和治疗的挑战:一个突出血管并发症和延迟识别的病例报告

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL
Bindira Adhikari, Biraj Niraula, Polina Dahal, Anil Suvedi, Gaurav Subedi
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引用次数: 0

摘要

Takayasu动脉炎是一种罕见的全身性炎症,主要影响中大动脉,主要发生在年轻的亚洲女性中,估计发病率为百万分之1-2。诊断是具有挑战性的,由于非特异性的早期症状,导致潜伏的临床过程,直到血管并发症出现。30岁女性,表现为进行性易疲劳4年。她最近出现视觉障碍、头痛和头晕。检查发现无法记录的血压和血管肿块。影像学显示血管受累,包括主动脉弓及其所有分支狭窄。现有的治疗方法可以缓解症状并减缓病情进展,但晚期诊断导致终身发病率,没有治疗持续性疲劳的方法。由于其非特异性早期症状和严重血管并发症的风险,TA给诊断带来了挑战。本病例强调了在有模糊全身性炎症症状的年轻女性中考虑TA的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Challenges in Diagnosis and Management of Takayasu Arteritis: A Case Report Highlighting Vascular Complications and Delayed Recognition

Challenges in Diagnosis and Management of Takayasu Arteritis: A Case Report Highlighting Vascular Complications and Delayed Recognition

Takayasu arteritis is a rare systemic inflammatory condition that primarily affects medium and large arteries, mainly in young Asian women with an estimated incidence of 1–2 per million. Diagnosis is challenging due to nonspecific early symptoms, resulting in an insidious clinical course until vascular complications arise. A 30-year female presented with progressive easy fatigue over 4 years. She developed recent visual disturbances, headaches, and dizziness. Examination revealed unrecordable blood pressures and vascular bruits. Imaging revealed vascular involvement including stenosis of arch of aorta and its all branches. The available treatments can ease symptoms and slow progression, but the late diagnosis caused lifelong morbidity, with no procedure to resolve persistent fatigue. TA poses diagnostic challenges due to its nonspecific early symptoms and risk of severe vascular complications. This case highlights the importance of considering TA in young women with vague systemic inflammatory symptoms.

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来源期刊
Clinical Case Reports
Clinical Case Reports MEDICINE, GENERAL & INTERNAL-
自引率
14.30%
发文量
1268
审稿时长
13 weeks
期刊介绍: Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).
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