0 CARDIAC & CARDIOVASCULAR SYSTEMS
N A Hasami, M Smulders, M W A Verkroost, W W L Li, N Saouti, F J H Nauta, G S C Geuzebroek, R H Heijmen
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摘要

目的:未经治疗的胸腹主动脉瘤病例是一项重大挑战,通常会导致严重的发病率和高死亡率。血管内治疗虽然前景广阔,但并不适合所有病例,尤其是年轻患者和胶原紊乱患者。本研究报告了 2015 年至 2023 年本学术医疗中心开放式胸腹主动脉瘤修补术的当代疗效:纳入2015年1月至2023年12月期间接受开放手术修复的所有胸腹主动脉瘤(Crawford-Safi I-V型)患者,包括择期和非择期病例。对患者特征、术中变量和术后结果进行了前瞻性记录和回顾性分析。主要终点是手术死亡率;次要终点包括脊髓损伤率、中风率、气管切开率、透析需求率,以及选择性和非选择性病例的结果比较:共纳入 190 名患者(146 例选择性/44 例非选择性),平均年龄为 63.8 岁(标准差 11.5),58% 为男性。手术死亡率为7.9%,其中择期手术死亡率为7.5%,非择期手术死亡率为9.1%。5.8%的患者在出院时仍有中风症状,3.7%的患者需要进行气管造口术。7.4%的患者在出院时出现脊髓损伤症状,2.1%的患者出现持续性截瘫,1.6%的患者出现截瘫。38.4%的患者出现急性肾损伤,其中6.9%需要透析,3.7%出院时仍需透析:结论:开放式胸腹主动脉瘤手术在多学科团队方法和严格围手术期规范的支持下,仍能有效管理这一复杂的患者群体,显示出较低的死亡率和严重并发症发生率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Contemporary outcomes of open thoraco-abdominal aortic repair: a single-centre experience.

Objectives: Untreated cases of thoraco-abdominal aortic aneurysms pose significant challenges, often leading to severe morbidity and high mortality. While promising, endovascular treatment is not suitable in all cases, particularly younger patients and those with collagen disorders. This study reports on the contemporary outcomes of open thoraco-abdominal aortic aneurysm repair at our academic medical centre from 2015 to 2023.

Methods: All patients with thoraco-abdominal aortic aneurysm (Crawford-Safi Types I-V), including elective and non-elective cases, who underwent open surgical repair between January 2015 and December 2023 were included. Patient characteristics, intraoperative variables and postoperative outcomes were prospectively recorded and analysed retrospectively. The primary end point was operative mortality; secondary end points included rates for spinal cord injury, stroke, tracheostomy, need for dialysis and a comparison of outcomes between elective and non-elective cases.

Results: 190 patients (146 elective/44 non-elective) were included, with a mean age of 63.8 years (standard deviation 11.5), and 58% were male. Operative mortality was 7.9%, with 7.5% in elective cases and 9.1% in non-elective cases. Stroke with persisting symptoms at discharge occurred in 5.8% of patients, and tracheostomy was required in 3.7%. Spinal cord injury symptoms were observed in 7.4%, with persistent paraparesis in 2.1% and paraplegia in 1.6% at discharge. Acute kidney injury occurred in 38.4% of patients, with 6.9% requiring dialysis and 3.7% continuing dialysis at discharge.

Conclusions: Open thoraco-abdominal aortic aneurysm surgery, supported by a multidisciplinary team approach and strict perioperative protocols, remains effective in managing this complex patient population, demonstrating low rates of mortality and severe complications.

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