[经皮超声引导下局部应用倍他米松治疗莫顿神经瘤]。

Q4 Medicine
Z Kh Plieva, M A Razin, A G Fedyakov, A V Baskov, A V Gorozhanin, A V Kuznetsov, O V Mukhina, E V Batalova
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引用次数: 0

摘要

莫顿神经瘤是最常见的周围神经单神经病变之一。主要临床表现为足部神经性疼痛综合征。目前,提出了许多治疗方法。尽管每种方法都有优点,但主要的缺点是有效性低,因疤痕相关并发症而加重症状,或手术侵入后并发症的发生率较高。目的:评价超声引导下局部应用倍他米松松解术治疗莫顿神经瘤的疗效。材料与方法:纳入女性患者14例,年龄24 ~ 56岁,平均44.7±6.4岁。分析疼痛综合征VAS评分(平均7.1±1.1)和神经性疼痛DN4评分(平均4.9±0.9)。超声成像估计神经瘤的定位和体积。神经瘤平均体积226±142 mm3。结果:平均随访12个月。14例患者中有12例疼痛强度显著降低至VAS评分1.1±0.6分,神经性疼痛回归至DN4评分0.5±0.5分。2例神经性疼痛6个月后复发,神经瘤扩大(分别为429和452mm3)。所有患者均无并发症。结论:超声引导下局部应用倍他米松进行莫顿神经瘤松解术是一种有效的微创治疗方法。选择该手术的标准可能是神经瘤体积小。需要进一步的研究来阐明该手术的适应症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Percutaneous ultrasound-guided neurolysis with local administration of betamethasone in the treatment of Morton's neuroma].

Morton's neuroma is one of the most common entrapment mononeuropathies of peripheral nerves. The main clinical manifestation is neuropathic pain syndrome in the foot. Currently, many methods of treatment are proposed. Despite the advantages of each method, the main disadvantages are low effectiveness, aggravation of symptoms due to scar-related complications, or relatively high incidence of complications following surgical invasion.

Objective: To evaluate the effectiveness of percutaneous ultrasound-guided neurolysis with local administration of betamethasone in patients with Morton's neuroma.

Material and methods: The study included 14 female patients aged 24-56 years (mean 44.7±6.4). We analyzed VAS scores of pain syndrome (mean 7.1±1.1) and DN4 scores of neuropathic pain (mean 4.9±0.9). Ultrasound imaging was performed to estimate localization and volume of neuroma. Mean volume of neuroma was 226±142 mm3.

Results: Mean follow-up was 12 months. In 12 out of 14 patients, there was a significant decrease in pain intensity to VAS score 1.1±0.6 and regression of neuropathic pain to DN4 score 0.5±0.5. In 2 cases, neuropathic pain recurred after 6 months with enlargement of neuromas (to 429 and 452 mm3). There were no complications in any patient.

Conclusion: Percutaneous ultrasound-guided neurolysis of Morton's neuroma with local administration of betamethasone is an effective and promising minimally invasive method. Selection criterion for this procedure may be small volume of neuroma. Further research is required to clarify the indications for this procedure.

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来源期刊
CiteScore
0.70
自引率
0.00%
发文量
75
期刊介绍: Scientific and practical peer-reviewed journal. This publication covers the theoretical, practical and organizational problems of modern neurosurgery, the latest advances in the treatment of various diseases of the central and peripheral nervous system. Founded in 1937. English version of the journal translates from Russian version since #1/2013.
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