促性腺激素刺激前测定的抗勒氏激素浓度与猎豹(Acinonyx jubatus)和家猫(Felis catus)随后卵巢反应的质量相关

IF 3.1 2区 生物学 Q2 REPRODUCTIVE BIOLOGY
Rhasaan T M Bovell, Pierre Comizzoli, Jennifer B Nagashima, Jenny Santiestevan, Adrienne E Crosier, Ned J Place
{"title":"促性腺激素刺激前测定的抗<s:1>勒氏激素浓度与猎豹(Acinonyx jubatus)和家猫(Felis catus)随后卵巢反应的质量相关","authors":"Rhasaan T M Bovell, Pierre Comizzoli, Jennifer B Nagashima, Jenny Santiestevan, Adrienne E Crosier, Ned J Place","doi":"10.1093/biolre/ioaf025","DOIUrl":null,"url":null,"abstract":"<p><p>Relationships between anti-Müllerian hormone concentrations and subsequent ovarian stimulation outcomes have been demonstrated in several mammalian species, but comprehensive reports are lacking in felids. Our objective was to characterize relationships between anti-Müllerian hormone concentrations and responses to exogenous gonadotropin stimulation in cheetahs and domestic cats. Blood samples collected before stimulation were used to measure serum anti-Müllerian hormone concentrations, which were compared to post-stimulation outcomes, including counts of retrievable oocytes or ovulation sites, oocyte quality, embryonic cleavage after in vitro fertilization, and progestogen concentrations. Anti-Müllerian hormone concentrations were also compared to outcomes in domestic cats induced to ovulate by mechanical stimulation of the vagina and cervix (simulated coitus). Greater anti-Müllerian hormone concentrations were associated with greater ovulatory response, progestogen production, and embryonic cleavage success among gonadotropin-treated cheetahs, and with greater ovulatory response among gonadotropin-treated domestic cats. Associations were moderated by age, with anti-Müllerian hormone concentration generally a greater determinant of these outcomes in older animals. Anti-Müllerian hormone concentrations alone could distinguish domestic cats with high and low ovulatory responses to exogenous hormones. However, this marker was unrelated to ovulatory response in domestic cats after simulated coitus. These results demonstrate the potential for anti-Müllerian hormone concentrations to predict responses of cheetahs and domestic cats to ovarian stimulation treatment commonly used in assisted reproductive technologies. Associations between anti-Müllerian hormone concentrations and ovarian stimulation outcomes in these species might reflect relationships between anti-Müllerian hormone concentration and antral follicle count or oocyte/embryo cellular function, as reported in other mammals; however, this remains to be tested.</p>","PeriodicalId":8965,"journal":{"name":"Biology of Reproduction","volume":" ","pages":"754-766"},"PeriodicalIF":3.1000,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Anti-Müllerian hormone concentration measured before gonadotropin stimulation is associated with quality of subsequent ovarian response in the cheetah (Acinonyx jubatus) and domestic cat (Felis catus)†.\",\"authors\":\"Rhasaan T M Bovell, Pierre Comizzoli, Jennifer B Nagashima, Jenny Santiestevan, Adrienne E Crosier, Ned J Place\",\"doi\":\"10.1093/biolre/ioaf025\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Relationships between anti-Müllerian hormone concentrations and subsequent ovarian stimulation outcomes have been demonstrated in several mammalian species, but comprehensive reports are lacking in felids. Our objective was to characterize relationships between anti-Müllerian hormone concentrations and responses to exogenous gonadotropin stimulation in cheetahs and domestic cats. Blood samples collected before stimulation were used to measure serum anti-Müllerian hormone concentrations, which were compared to post-stimulation outcomes, including counts of retrievable oocytes or ovulation sites, oocyte quality, embryonic cleavage after in vitro fertilization, and progestogen concentrations. Anti-Müllerian hormone concentrations were also compared to outcomes in domestic cats induced to ovulate by mechanical stimulation of the vagina and cervix (simulated coitus). Greater anti-Müllerian hormone concentrations were associated with greater ovulatory response, progestogen production, and embryonic cleavage success among gonadotropin-treated cheetahs, and with greater ovulatory response among gonadotropin-treated domestic cats. Associations were moderated by age, with anti-Müllerian hormone concentration generally a greater determinant of these outcomes in older animals. Anti-Müllerian hormone concentrations alone could distinguish domestic cats with high and low ovulatory responses to exogenous hormones. However, this marker was unrelated to ovulatory response in domestic cats after simulated coitus. These results demonstrate the potential for anti-Müllerian hormone concentrations to predict responses of cheetahs and domestic cats to ovarian stimulation treatment commonly used in assisted reproductive technologies. Associations between anti-Müllerian hormone concentrations and ovarian stimulation outcomes in these species might reflect relationships between anti-Müllerian hormone concentration and antral follicle count or oocyte/embryo cellular function, as reported in other mammals; however, this remains to be tested.</p>\",\"PeriodicalId\":8965,\"journal\":{\"name\":\"Biology of Reproduction\",\"volume\":\" \",\"pages\":\"754-766\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-04-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biology of Reproduction\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1093/biolre/ioaf025\",\"RegionNum\":2,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"REPRODUCTIVE BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biology of Reproduction","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1093/biolre/ioaf025","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"REPRODUCTIVE BIOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

勒氏激素(AMH)浓度与随后的卵巢刺激结果之间的关系已在几种哺乳动物物种中得到证实,但在猫科动物中缺乏全面的报道。本研究的目的是表征AMH浓度与猎豹和家猫对外源性促性腺激素刺激的反应之间的关系。刺激前采集的血液样本用于测量血清AMH浓度,并将其与刺激后的结果进行比较,包括可回收卵母细胞或排卵部位的计数、卵母细胞质量、体外受精后的胚胎卵裂和孕激素浓度。我们还比较了经阴道和子宫颈机械刺激(模拟交媾)诱导的家猫的AMH浓度和排卵结果。在促性腺激素治疗的猎豹中,更高的AMH浓度与更高的排卵反应、孕激素产生和胚胎切割成功率有关,而在促性腺激素治疗的家猫中,更高的AMH浓度与更高的排卵反应有关。这种关联随着年龄的增长而减弱,在老年动物中,AMH浓度通常是这些结果的更大决定因素。仅使用AMH浓度,就可以区分家猫对外源激素的高和低排卵反应。然而,该标记与模拟交媾后家猫的排卵反应无关。这些结果表明,AMH浓度有可能预测猎豹和家猫对辅助生殖技术中常用的卵巢刺激治疗的反应。在这些物种中,AMH浓度与卵巢刺激结果之间的关联可能源于AMH浓度与窦卵泡计数或卵母细胞/胚胎细胞功能之间的关系,正如在其他哺乳动物中报道的那样;然而,这还有待检验。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Anti-Müllerian hormone concentration measured before gonadotropin stimulation is associated with quality of subsequent ovarian response in the cheetah (Acinonyx jubatus) and domestic cat (Felis catus)†.

Relationships between anti-Müllerian hormone concentrations and subsequent ovarian stimulation outcomes have been demonstrated in several mammalian species, but comprehensive reports are lacking in felids. Our objective was to characterize relationships between anti-Müllerian hormone concentrations and responses to exogenous gonadotropin stimulation in cheetahs and domestic cats. Blood samples collected before stimulation were used to measure serum anti-Müllerian hormone concentrations, which were compared to post-stimulation outcomes, including counts of retrievable oocytes or ovulation sites, oocyte quality, embryonic cleavage after in vitro fertilization, and progestogen concentrations. Anti-Müllerian hormone concentrations were also compared to outcomes in domestic cats induced to ovulate by mechanical stimulation of the vagina and cervix (simulated coitus). Greater anti-Müllerian hormone concentrations were associated with greater ovulatory response, progestogen production, and embryonic cleavage success among gonadotropin-treated cheetahs, and with greater ovulatory response among gonadotropin-treated domestic cats. Associations were moderated by age, with anti-Müllerian hormone concentration generally a greater determinant of these outcomes in older animals. Anti-Müllerian hormone concentrations alone could distinguish domestic cats with high and low ovulatory responses to exogenous hormones. However, this marker was unrelated to ovulatory response in domestic cats after simulated coitus. These results demonstrate the potential for anti-Müllerian hormone concentrations to predict responses of cheetahs and domestic cats to ovarian stimulation treatment commonly used in assisted reproductive technologies. Associations between anti-Müllerian hormone concentrations and ovarian stimulation outcomes in these species might reflect relationships between anti-Müllerian hormone concentration and antral follicle count or oocyte/embryo cellular function, as reported in other mammals; however, this remains to be tested.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Biology of Reproduction
Biology of Reproduction 生物-生殖生物学
CiteScore
6.30
自引率
5.60%
发文量
214
审稿时长
1 months
期刊介绍: Biology of Reproduction (BOR) is the official journal of the Society for the Study of Reproduction and publishes original research on a broad range of topics in the field of reproductive biology, as well as reviews on topics of current importance or controversy. BOR is consistently one of the most highly cited journals publishing original research in the field of reproductive biology.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信