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用于靶向光热化疗的低氧响应胆红素超分子纳米药物。

IF 4.2 2区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY
Chemical Communications Pub Date : 2025-01-29 DOI:10.1039/D4CC06433J
Yu Xie, Liangshun Zheng, Tingting Chen and Yue Ding
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引用次数: 0

摘要

基于主客体识别构建了一种增强HepG2细胞系细胞摄取的胆红素超分子纳米前药（SCBR/TPZ），为设计一种对HepG2具有协同作用的低氧响应的糖靶向光热化疗（PTT-CT）胆红素超分子纳米前药提供了一种创新策略。
本文章由计算机程序翻译，如有差异，请以英文原文为准。

Hypoxia-responsive bilirubin supramolecular nanoprodrugs for targeted photothermal-chemotherapy†

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Hypoxia-responsive bilirubin supramolecular nanoprodrugs for targeted photothermal-chemotherapy†

A bilirubin supramolecular nanoprodrug (SCBR/TPZ) with enhanced cellular uptake towards the HepG2 cell line was constructed based on host–guest recognition, which provided an innovative strategy to design a hypoxia-responsive BR supramolecular nanoprodrug for lactose-targeted photothermal-chemotherapy (PTT-CT) with a synergistic effect towards HepG2.

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来源期刊
Chemical Communications
Chemical Communications 化学-化学综合
CiteScore
8.60
自引率
4.10%
发文量
2705
审稿时长
1.4 months
期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.
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