中西医结合治疗阿尔茨海默病神经精神症状一例报告

IF 1.7 Q2 Medicine

Advances in integrative medicine Pub Date : 2024-12-01 DOI:10.1016/j.aimed.2024.08.008

Renée Hahn

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引用次数: 0

摘要

中草药（CHM）和针灸是中医（TCM）综合医疗保健系统的基本方式，研究表明它们对治疗神经精神症状（NPS）有效。这些治疗方法目前仅限于阿尔茨海默病（AD）和其他类型的痴呆症患者。本研究报告成功治疗老年女性患者躁动，失眠，抑郁，冷漠和焦虑与AD。一位86岁的老年妇女住在一家养老院，她患有严重的躁动、攻击行为、失眠和焦虑以及AD，在她生命的剩余近3年里，她接受了中医和针灸治疗。数据从护士的日志记录和图表中收集，以评估治疗效果。在使用CHM前的90天里，她总共有30次记录在案的躁动发作，对总共45次的药物治疗没有反应。这些症状包括身体攻击、失眠、大喊大叫和一阵阵哭泣。在开始中西医结合治疗后的90天内，有记录的躁动发作7次，共给予药物6次。结论中药联合针刺可减轻AD患者躁动及失眠、抑郁、躁动、冷漠、焦虑等NPS，改善AD患者的生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Treatment of neuropsychiatric symptoms in Alzheimer’s disease with traditional Chinese medicine: An integrative medicine case report

Background

Research on Chinese herbal medicine (CHM) and acupuncture, fundamental modalities of the comprehensive medical system of healthcare known as Traditional Chinese Medicine (TCM), suggest that they are effective for treating neuropsychiatric symptoms (NPS). Use of these treatments is currently limited for patients with Alzheimer’s disease (AD) and other types of dementia. This study reports the successful treatment of an elderly female patient with agitation, insomnia, depression, apathy, and anxiety relating to AD.

Patient Presentation

An 86-year-old woman living in a nursing home who had severe agitation, aggressive behaviors, insomnia, and anxiety along with AD was treated with CHM and acupuncture for the remaining nearly 3 years of her life. Data was gathered from the nurses’ log notes and charts created to evaluate treatment efficacy.

In the 90 days before CHM was administered, she had a total of 30 documented episodes of agitation not responsive to pharmaceutical medications given a total of 45 times. The episodes included physical aggression, insomnia, shouting, and bouts of crying. In the 90 days after starting CHM, she had a documented 7 episodes of agitation and was given pharmaceuticals a total of 6 times.

Conclusion

CHM and acupuncture may alleviate agitation and other NPS such as insomnia, depression, agitation, apathy, and anxiety, and improve the quality of life in patients with AD.

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来源期刊

Advances in integrative medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

3.20

自引率

11.80%

发文量

审稿时长

15 weeks

期刊介绍： Advances in Integrative Medicine (AIMED) is an international peer-reviewed, evidence-based research and review journal that is multi-disciplinary within the fields of Integrative and Complementary Medicine. The journal focuses on rigorous quantitative and qualitative research including systematic reviews, clinical trials and surveys, whilst also welcoming medical hypotheses and clinically-relevant articles and case studies disclosing practical learning tools for the consulting practitioner. By promoting research and practice excellence in the field, and cross collaboration between relevant practitioner groups and associations, the journal aims to advance the practice of IM, identify areas for future research, and improve patient health outcomes. International networking is encouraged through clinical innovation, the establishment of best practice and by providing opportunities for cooperation between organisations and communities.