镍催化PH/CF交叉偶联反应生成三芳基膦

IF 1.5 4区化学 Q3 CHEMISTRY, ORGANIC

Tetrahedron Letters Pub Date : 2025-01-30 DOI:10.1016/j.tetlet.2024.155445

Meng-Ting Xiang , Lei Fan , Qian Xu , Li Zhang , Shuai Wang , Hong Zhong , Jia Yang

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引用次数: 0

摘要

本研究公开了一种镍催化的单氟芳烃或多氟芳烃与二苯基膦通过CF键功能化构建C(sp2)P键的偶联反应。该反应可成功制得相应的三芳基膦或氟化三芳基膦化合物，收率从好到高，为通过形成CP键合成含氟有机膦化合物提供了一种新方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Formation of triarylphosphines via PH/CF cross coupling reactions catalyzed by nickel

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Formation of triarylphosphines via PH/CF cross coupling reactions catalyzed by nickel

Herein, a nickel-catalyzed coupling reaction of monofluoroarenes or polyfluoroarenes with diphenyl phosphine to construct C(sp²)P bond through CF bond functionalization is disclosed. The reaction can be carried out successfully to produce the corresponding triarylphosphine or fluorinated triarylphosphine compounds with good to high yields, providing a new method for the synthesis of fluorine-containing organophosphine compounds via the formation of CP bond.

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来源期刊

Tetrahedron Letters 化学-有机化学

CiteScore

3.50

自引率

5.60%

发文量

521

审稿时长

28 days

期刊介绍： Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.