纳米颗粒输送治疗结肠癌的诊断创新和治疗潜力

IF 5.45 Q1 Physics and Astronomy
Ayushmaan Roy , Mohammad Adnan Raza , Vijayalakshmi Ghosh , Ajazuddin
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引用次数: 0

摘要

结直肠癌(Colorectal cancer, CRC)是一种常见的恶性疾病,影响着全世界的人们,尤其是那些50岁或以上的人群,他们患这种疾病的几率更高。尽管诊断技术和早期筛查的改进已经导致癌症相关死亡的减少,但仍然迫切需要新的治疗方法。科学家们很快认识到纳米粒子(NPs)通过提高药物的精确性、溶解度和可及性,在提高诊断和治疗的准确性、有效性和可获得性方面的重要性。纳米颗粒(NPs)显示出降低药物毒性和特异性靶向恶性肿瘤的潜力,从而减少不良副作用。本研究综合评估了使用各种纳米产品检测和治疗结直肠癌(CRC)的实用性。本研究通过对NPs的潜力进行全面分析,增加了CRC管理的范式变化。将尖端纳米技术纳入结直肠癌治疗可以带来重大变化,提供一种开发个性化和精确治疗的方法。这一分析强调,鉴于结直肠癌(CRC)的全球影响,需要使用新的和创造性的方法来满足对先进疗法的持续需求。随着对有效治疗的需求不断增加,研究纳米产品成为一个新的研究领域,对结直肠癌的治疗具有重要意义。这凸显了在这一快速发展的领域进行持续研究和开发的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diagnostic innovations and therapeutic potential of nanoparticulate delivery for colon cancer
Colorectal cancer (CRC) is a frequently occurring malignant disease that affects people worldwide, especially those who are 50 years old or older and have a higher chance of developing the disease. Although improvements in diagnostic techniques and early screening have led to a decrease in cancer-related deaths, there remains an urgent want for novel treatment approaches. Scientists are quickly acknowledging the importance of nanoparticles (NPs) in improving the accuracy, effectiveness, and availability of diagnostic and treatments by enhancing the precision, solubility, and accessibility of pharmaceuticals. Nanoparticles (NPs) show potential in reducing medication toxicity and specifically targeting malignant tumors, therefore decreasing adverse side effects. This study comprehensively evaluates the practicality of using various nano products to detect and treat colorectal cancer (CRC). This study adds to the paradigm change in CRC management by conducting a thorough analysis of the potential of NPs. Incorporating cutting-edge nanotechnologies into CRC treatments can bring about significant changes, providing a way to develop individualized and precise therapies. This analysis highlights the need to use new and creative methods to satisfy the ongoing requirement for advanced therapies in light of the worldwide effect of colorectal cancer (CRC). With the increasing need for effective treatments, investigating nanoproducts becomes a new area of study with significant implications for CRC management. This highlights the need for ongoing research and development in this rapidly evolving sector.
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来源期刊
Nano-Structures & Nano-Objects
Nano-Structures & Nano-Objects Physics and Astronomy-Condensed Matter Physics
CiteScore
9.20
自引率
0.00%
发文量
60
审稿时长
22 days
期刊介绍: Nano-Structures & Nano-Objects is a new journal devoted to all aspects of the synthesis and the properties of this new flourishing domain. The journal is devoted to novel architectures at the nano-level with an emphasis on new synthesis and characterization methods. The journal is focused on the objects rather than on their applications. However, the research for new applications of original nano-structures & nano-objects in various fields such as nano-electronics, energy conversion, catalysis, drug delivery and nano-medicine is also welcome. The scope of Nano-Structures & Nano-Objects involves: -Metal and alloy nanoparticles with complex nanostructures such as shape control, core-shell and dumbells -Oxide nanoparticles and nanostructures, with complex oxide/metal, oxide/surface and oxide /organic interfaces -Inorganic semi-conducting nanoparticles (quantum dots) with an emphasis on new phases, structures, shapes and complexity -Nanostructures involving molecular inorganic species such as nanoparticles of coordination compounds, molecular magnets, spin transition nanoparticles etc. or organic nano-objects, in particular for molecular electronics -Nanostructured materials such as nano-MOFs and nano-zeolites -Hetero-junctions between molecules and nano-objects, between different nano-objects & nanostructures or between nano-objects & nanostructures and surfaces -Methods of characterization specific of the nano size or adapted for the nano size such as X-ray and neutron scattering, light scattering, NMR, Raman, Plasmonics, near field microscopies, various TEM and SEM techniques, magnetic studies, etc .
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