{"title":"冲击波对骨组织肿瘤作用的数值研究","authors":"Galina Eremina , Alexey Smolin","doi":"10.1016/j.prostr.2024.11.014","DOIUrl":null,"url":null,"abstract":"<div><div>Cancer diseases significantly worsen the quality of life of people. Recent studies have shown that relatively small values of compressive stress over 40 kPa lead to growth and migration of cancer cells, while large amplitude can lead to tumour growth arrest. In this work, a mesomodel of a spherical cancer tumour placed in a cubic bone matrix was developed. The influence of loads on the stress-strain state (hydrostatic pressure) is analyzed. The working range of therapy shock wave treatment for stopping tumor growth without damaging surrounding tissues has been determined.</div></div>","PeriodicalId":20518,"journal":{"name":"Procedia Structural Integrity","volume":"65 ","pages":"Pages 92-96"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Numerical study of the shock wave effect on tumour in bone tissue\",\"authors\":\"Galina Eremina , Alexey Smolin\",\"doi\":\"10.1016/j.prostr.2024.11.014\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Cancer diseases significantly worsen the quality of life of people. Recent studies have shown that relatively small values of compressive stress over 40 kPa lead to growth and migration of cancer cells, while large amplitude can lead to tumour growth arrest. In this work, a mesomodel of a spherical cancer tumour placed in a cubic bone matrix was developed. The influence of loads on the stress-strain state (hydrostatic pressure) is analyzed. The working range of therapy shock wave treatment for stopping tumor growth without damaging surrounding tissues has been determined.</div></div>\",\"PeriodicalId\":20518,\"journal\":{\"name\":\"Procedia Structural Integrity\",\"volume\":\"65 \",\"pages\":\"Pages 92-96\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Procedia Structural Integrity\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S245232162401062X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Procedia Structural Integrity","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S245232162401062X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Numerical study of the shock wave effect on tumour in bone tissue
Cancer diseases significantly worsen the quality of life of people. Recent studies have shown that relatively small values of compressive stress over 40 kPa lead to growth and migration of cancer cells, while large amplitude can lead to tumour growth arrest. In this work, a mesomodel of a spherical cancer tumour placed in a cubic bone matrix was developed. The influence of loads on the stress-strain state (hydrostatic pressure) is analyzed. The working range of therapy shock wave treatment for stopping tumor growth without damaging surrounding tissues has been determined.
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