女性神经源性应激性尿失禁的综合治疗

Vicktor Bruno Pereira Pinto, Luísa Resende Tenório de Albuquerque, Bernardo Sachet de Andrade, Cristiano Mendes Gomes
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引用次数: 0

摘要

回顾的目的:神经源性压力性尿失禁(NSUI)的管理面临着巨大的挑战,由于潜在条件的复杂性,患者对治疗反应的可变性,以及支持各种治疗方案的证据有限。鉴于膀胱和肠道功能障碍的共存以及考虑个体社会环境的必要性,准确的诊断和量身定制的干预措施至关重要。这篇综述的目的是更新目前女性NSUI手术治疗的策略,强调个体化、以患者为中心的方法的重要性。最新发现:现有的关于NSUI的科学文献在数量和质量上仍然有限,大多数研究是回顾性的,涉及的患者群体小,随访时间短。这些研究往往以不同的群体和不同的成功定义为特征,使结果解释复杂化。人工尿道中吊带和人工尿道括约肌(AUS)机器人植入术的结果令人满意,而自体筋膜吊带仍然被认为是一种可靠的选择。尽管AUS有疗效,但与器械相关的并发症仍然令人担忧。其他治疗方法,如填充剂和可调节的自制装置,都显示出有限的成功。摘要:多学科、针对患者的治疗方法对于治疗女性NSUI至关重要,旨在提高生活质量和保护尿路功能。定期随访对于监测和解决潜在并发症至关重要,包括尿失禁率下降和其他与治疗相关的不良事件。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comprehensive management of neurogenic stress urinary incontinence in women
Purpose of review: The management of neurogenic stress urinary incontinence (NSUI) in women presents significant challenges due to the complexity of underlying conditions, the variability in patient responses to treatments, and the limited evidence supporting various therapeutic options. Accurate diagnosis and tailored interventions are crucial, given the coexistence of bladder and bowel dysfunctions and the necessity to consider individual social circumstances. This review aims to update the current strategies for the surgical management of NSUI in women, emphasizing the importance of an individualized, patient-centered approach.
Recent findings: The existing scientific literature on NSUI remains limited in both volume and quality, with most studies being retrospective, involving small patient populations and short follow-up periods. These studies often feature heterogeneous groups and varied definitions of success, complicating result interpretation. Promising outcomes have been observed with synthetic midurethral slings and robotic implantation of artificial urinary sphincters (AUS), while autologous fascial slings continue to be regarded as a reliable option. Despite the efficacy of the AUS, device-related complications remain a concern. Other treatments, such as bulking agents and adjustable continence devices, have shown limited success.
Summary: A multidisciplinary, patient-tailored approach is essential for managing NSUI in women, aiming to enhance quality of life and protect urinary tract function. Regular follow-up is crucial to monitor and address potential complications, including declining continence rates and other treatment-related adverse events.
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