纳米载体在皮肤癌治疗:新兴的药物输送方法和创新

Laxmi A. Jadhav, Satish K. Mandlik
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引用次数: 0

摘要

皮肤癌是一个日益严重的全球健康问题,发病率不断上升,尤其是在高加索人群中。它是最常见的恶性肿瘤,在世界范围内显著导致死亡率和生活质量下降。虽然手术干预仍然是主要的治疗方法,但迫切需要创新的策略来降低与该疾病相关的发病率和死亡率。随着皮肤癌的负担持续增长,医学界越来越多地探索新的治疗方法来改善患者的预后。纳米技术为治疗皮肤癌带来了新的可能性,在靶向药物输送、先进成像和诊断方面提供了优势。纳米材料在皮肤病学中特别有用,因为它们增强了治疗剂的渗透和保留,同时最小化了副作用。人们研究了各种纳米材料在治疗包括癌症在内的皮肤疾病方面的潜力。本文综述了纳米技术在皮肤癌治疗中的作用,重点介绍了用于精确递送药物的纳米载体的开发和设计。我们还讨论了纳米技术相对于传统治疗的优势,例如提高生物利用度和靶向作用。此外,我们还探讨了与基于纳米载体的癌症和皮肤癌治疗相关的临床试验、专利和FDA批准的产品,重点介绍了该领域的进展。结论纳米技术在皮肤癌治疗中具有革命性的前景。随着研究的进展,预计将出现更有效、更个性化的治疗方法,最终改善患者的预后。将纳米技术整合到临床实践中可以提高护理标准,为治疗皮肤癌提供新的希望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nanocarriers in skin cancer treatment: Emerging drug delivery approaches and innovations

Background

Skin cancer is a growing global health issue, with rising incidence rates, particularly among Caucasian populations. It is the most common malignancy, contributing significantly to mortality and decreased quality of life worldwide. While surgical interventions remain the primary treatment, there is a pressing need for innovative strategies to reduce the morbidity and mortality associated with the disease. As the burden of skin cancer continues to grow, the medical community is increasingly exploring novel therapeutic approaches to improve patient outcomes.

Main body

Nanotechnology has introduced new possibilities for treating skin cancer, offering advantages in targeted drug delivery, advanced imaging, and diagnostics. Nanomaterials are especially useful in dermatology, as they enhance the penetration and retention of therapeutic agents while minimizing side effects. Various nanomaterials have been studied for their potential in treating skin disorders, including cancer. This review examines the role of nanotechnology in skin cancer treatment, focusing on the development and design of nanocarriers for the precise delivery of drugs. We also discuss the advantages of nanotechnology over traditional treatments, such as improved bioavailability and targeted action. Additionally, we explore clinical trials, patents and FDA approved products related to nanocarrier-based treatments for cancer and skin cancer, highlighting advancements in the field.

Conclusion

Nanotechnology holds significant promise in revolutionizing skin cancer treatment. As research progresses, it is expected that more effective, personalized therapies will emerge, ultimately improving patient outcomes. Integrating nanotechnology into clinical practice could elevate the standard of care, offering new hope in managing skin cancer.
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