2010 - 2020年美国膝关节软骨修复手术趋势

Akshar P. Thakkar , Ting Zhang , Michael Bodine , Aaron A. Bare , Michael B. Ellman , Sanjeev Bhatia , Andreas H. Gomoll , Brian J. Chilelli
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引用次数: 0

摘要

膝关节软骨损伤的手术干预可以预防有症状患者的退行性变。本研究旨在分析2010-2020年美国4种不同膝关节软骨修复手术的趋势、人口统计和年发病率。方法查询PearlDiver数据库2010-2020年接受膝关节微骨折、自体软骨细胞植入(ACI)、自体骨软骨移植(OAT)和同种异体骨软骨移植(OCA)手术的患者。采用Student t检验和χ2检验对数据趋势进行统计比较和分析。回归模型和复合年增长率进一步评估了每个程序的趋势。结果2010-2020年共纳入220,674例患者。微断裂发生率下降62.4% (P <;措施)。OCA发病率呈上升趋势(37.7%;P = 0.065),而OAT程序显著减少(53.9%;P & lt;措施)。ACI手术数量保持相对稳定(增加11.2%;p = .847)。结论2010-2020年美国微骨折发生率明显下降。OCA病例的发病率呈上升趋势,而OAT病例的数量则明显下降。除了2017-2019年的增加外,每年进行的ACI病例数量在研究期间没有显着变化。与其他软骨手术相比,微骨折手术适用于年龄较大的患者。与女性相比,男性更容易接受4次软骨保留手术。应该在其他大型健康数据库中进行类似的研究,以确认这些趋势在美国各地的外部有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Trends in knee cartilage repair procedures in the United States, 2010 to 2020

Introduction

Surgical intervention of knee articular cartilage injuries may prevent degeneration in symptomatic patients.

Objectives

This study aims to analyze trends, demographics, and yearly incidence of 4 different knee cartilage repair procedures in the United States from 2010-2020.

Methods

The PearlDiver database was queried for patients who underwent knee microfracture, autologous chondrocyte implantation (ACI), osteochondral autograft transfer (OAT), and osteochondral allograft (OCA) transplantation procedures from 2010-2020. Student t and χ2 tests were used for statistical comparisons and analysis of data trends. Regression models and compound annual growth rates further assessed the trends of each procedure.

Results

A total of 220,674 patients from 2010-2020 were included in this study. Microfracture incurred a 62.4% decrease in occurrence (P < .001). Incidence of OCA trended upward (37.7%; P = .065) while OAT procedures significantly decline (53.9%; P < .001). ACI procedure numbers remained relatively stable (11.2% increase; P = .847).

Conclusions

The incidence of microfracture significantly decreased in the United States from 2010-2020. There was a positive trend in the incidence of OCA cases, while the number of OAT cases decreased significantly. The number of ACI cases performed per year did not change significantly over the study period with the exception of an increase from 2017-2019. Microfracture procedures were performed in an older patient population than the other cartilage procedures. Males were more likely to undergo the 4 cartilage preservation surgeries compared to females. Similar studies should be carried out in other large health databases to confirm the external validity of these trends across the United States.
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