通过新技术减少危害

C.R. Pudney
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引用次数: 0

摘要

NPS在检测和监测方面提出了独特的挑战。这些药物的结构变化很快,通常以混合物形式存在,并以复杂的基质走私,包括纸、织物、草药材料和电子烟液体。由于这些原因,对NPS进行即时现场测试并不常见。我们已经证明了光谱指纹图谱,即样品的激发发射矩阵,可以用来区分NPS并提供浓度信息。此外,我们已经克服了具有复杂背景的光谱信号卷积的挑战,例如,纸/织物浸泡的样品。将这些技术结合起来,我们开发了一种手持式电池供电设备,可用于在非常广泛的物理矩阵上对大量NPS进行即时推定检测,也可直接从平板电脑中识别NPS。我们展示了该装置在减少合成大麻素(SCs)流入监狱,识别蒸汽液体和直接从未打开的电子烟笔中识别SCs以及识别苯二氮卓片方面的效用。通过这项技术,我们的目标是让那些本来不会参与减少伤害服务的用户能够识别出NPS。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Enabling Harm Reduction through New Technology
NPS present unique challenges in detection and monitoring. The structures of these drugs change rapidly, are often present in mixtures and are smuggled on complex matrices including paper, fabric, herb material and in vape liquid. For these reasons, instant field-based testing for NPS is not common. We have demonstrated that spectral fingerprinting, the excitation emission matrix of a sample, can be used to discriminate NPS and provide information on concentration. Moreover, we have overcome the challenge in the convolution of spectral signals with complex backgrounds that arise from e.g., paper/fabric-soaked samples. With these technologies combined, we have developed a hand-held, battery-operated device that can be used for the instant presumptive detection of a large range of NPS on a very broad range of physical matrices, as well as identification of NPS directly from tablets. We show the utility of this device in decreasing the flow of synthetic cannabinoids (SCs) into prisons, the identification of SCs in vape liquid and direct from unopened vape pens, and the identification of benzodiazepine tablets. Through this technology, we aim to enable the identification of NPS by users who would otherwise not engage in harm reduction services.
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来源期刊
Emerging trends in drugs, addictions, and health
Emerging trends in drugs, addictions, and health Pharmacology, Psychiatry and Mental Health, Forensic Medicine, Drug Discovery, Pharmacology, Toxicology and Pharmaceutics (General)
CiteScore
2.40
自引率
0.00%
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0
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