母系和子代犬新孢子虫血清阳性对子代出生体重、存活率、繁殖性能和流产影响的纵向研究

IF 1.4 Q3 PARASITOLOGY

Veterinary parasitology, regional studies and reports Pub Date : 2025-02-01 DOI:10.1016/j.vprsr.2025.101206

Amir Abbas Mohieddini , Mohammad Mahdi Delavari , Reza Hemmati Baghbanani , Vahid Akbarinejad

{"title":"母系和子代犬新孢子虫血清阳性对子代出生体重、存活率、繁殖性能和流产影响的纵向研究","authors":"Amir Abbas Mohieddini , Mohammad Mahdi Delavari , Reza Hemmati Baghbanani , Vahid Akbarinejad","doi":"10.1016/j.vprsr.2025.101206","DOIUrl":null,"url":null,"abstract":"<div><div>Neospora caninum (N. caninum) is known as a source of economic losses due to causing abortion in cows. Additionally, it is well-established that this parasite can be vertically transmitted from the dam to the fetus through placenta. There is, however, little and contradictory information about whether transplacental infection of the offspring during prenatal period could impair its survival and reproductive performance during postnatal period, and the current study was conducted to address this issue. To this end, seropositivity of heifer dams (n = 430) and their offspring were ascertained at the age of 12 and 3 months, respectively. Based on the serologic results, there were four categories of female offspring including: 1) seronegative offspring born to seronegative dams (n = 183), 2) seropositive offspring born to seronegative dams (n = 59), 3) seronegative offspring born to seropositive dams (n = 29), and 4) seropositive offspring born to seropositive dams (n = 30). The birth weight, survival, reproductive performance and abortion of these offspring were studied from birth to culling. Maternal seropositivity was positively associated with offspring seropositivity (P < 0.05). Birth weight did not differ among offspring in various categories (P > 0.05). Seropositive offspring born to seronegative dams and seronegative offspring born to seropositive dams had inferior cumulative reproductive performance over life as compared to seronegative offspring born to seronegative dams (P < 0.05). Seropositive offspring had greater cumulative abortion risk and shorter lifespan than seronegative offspring regardless of their maternal serologic condition (P < 0.05). In conclusion, the present study showed that maternal seropositivity for N. caninum increased the risk of seropositivity in the offspring, and seropositive offspring had increased abortion risk and decreased longevity. Maternal seropositivity for N. caninum could have developmental effects on cumulative reproductive performance of the offspring that were not vertically infected.</div></div>","PeriodicalId":23600,"journal":{"name":"Veterinary parasitology, regional studies and reports","volume":"58 ","pages":"Article 101206"},"PeriodicalIF":1.4000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A longitudinal study on the effects of maternal and offspring seropositivity for Neospora caninum on birth weight, survival, reproductive performance and abortion in the offspring\",\"authors\":\"Amir Abbas Mohieddini , Mohammad Mahdi Delavari , Reza Hemmati Baghbanani , Vahid Akbarinejad\",\"doi\":\"10.1016/j.vprsr.2025.101206\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Neospora caninum (N. caninum) is known as a source of economic losses due to causing abortion in cows. Additionally, it is well-established that this parasite can be vertically transmitted from the dam to the fetus through placenta. There is, however, little and contradictory information about whether transplacental infection of the offspring during prenatal period could impair its survival and reproductive performance during postnatal period, and the current study was conducted to address this issue. To this end, seropositivity of heifer dams (n = 430) and their offspring were ascertained at the age of 12 and 3 months, respectively. Based on the serologic results, there were four categories of female offspring including: 1) seronegative offspring born to seronegative dams (n = 183), 2) seropositive offspring born to seronegative dams (n = 59), 3) seronegative offspring born to seropositive dams (n = 29), and 4) seropositive offspring born to seropositive dams (n = 30). The birth weight, survival, reproductive performance and abortion of these offspring were studied from birth to culling. Maternal seropositivity was positively associated with offspring seropositivity (P < 0.05). Birth weight did not differ among offspring in various categories (P > 0.05). Seropositive offspring born to seronegative dams and seronegative offspring born to seropositive dams had inferior cumulative reproductive performance over life as compared to seronegative offspring born to seronegative dams (P < 0.05). Seropositive offspring had greater cumulative abortion risk and shorter lifespan than seronegative offspring regardless of their maternal serologic condition (P < 0.05). In conclusion, the present study showed that maternal seropositivity for N. caninum increased the risk of seropositivity in the offspring, and seropositive offspring had increased abortion risk and decreased longevity. Maternal seropositivity for N. caninum could have developmental effects on cumulative reproductive performance of the offspring that were not vertically infected.</div></div>\",\"PeriodicalId\":23600,\"journal\":{\"name\":\"Veterinary parasitology, regional studies and reports\",\"volume\":\"58 \",\"pages\":\"Article 101206\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Veterinary parasitology, regional studies and reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2405939025000139\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PARASITOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Veterinary parasitology, regional studies and reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2405939025000139","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PARASITOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

犬新孢子虫（N. caninum）因引起奶牛流产而被认为是经济损失的来源。此外，已经证实这种寄生虫可以通过胎盘从母体垂直传播给胎儿。然而，关于产前经胎盘感染的后代是否会影响其产后的生存和繁殖性能，目前的研究很少且相互矛盾，本研究旨在解决这一问题。为此，研究人员分别在12月龄和3月龄时测定了430头小母牛及其后代的血清阳性。根据血清学结果，雌性后代分为4类：1)血清阴性母鼠（183例），2)血清阴性母鼠（59例），3)血清阳性母鼠（29例），4)血清阳性母鼠（30例）。从出生到淘汰，对这些后代的出生体重、存活率、繁殖性能和流产率进行了研究。母体血清阳性与子代血清阳性呈正相关(P <；0.05)。在不同种类的后代中，出生体重没有差异(P >；0.05)。与血清阴性母鼠所生的血清阴性后代相比，血清阴性母鼠所生的血清阳性后代和血清阴性母鼠所生的血清阴性后代终生累积生殖性能较差(P <；0.05)。血清阳性子代与血清阴性子代相比，不论母体血清学状况如何，其累积流产风险更高，寿命更短(P <；0.05)。综上所述，本研究表明，母鼠血清阳性会增加子代血清阳性的风险，血清阳性子代流产风险增加，寿命降低。母鼠血清阳性可能对未垂直感染的后代的累积繁殖性能有发育影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

A longitudinal study on the effects of maternal and offspring seropositivity for Neospora caninum on birth weight, survival, reproductive performance and abortion in the offspring

查看原文本刊更多论文

A longitudinal study on the effects of maternal and offspring seropositivity for Neospora caninum on birth weight, survival, reproductive performance and abortion in the offspring

Neospora caninum (N. caninum) is known as a source of economic losses due to causing abortion in cows. Additionally, it is well-established that this parasite can be vertically transmitted from the dam to the fetus through placenta. There is, however, little and contradictory information about whether transplacental infection of the offspring during prenatal period could impair its survival and reproductive performance during postnatal period, and the current study was conducted to address this issue. To this end, seropositivity of heifer dams (n = 430) and their offspring were ascertained at the age of 12 and 3 months, respectively. Based on the serologic results, there were four categories of female offspring including: 1) seronegative offspring born to seronegative dams (n = 183), 2) seropositive offspring born to seronegative dams (n = 59), 3) seronegative offspring born to seropositive dams (n = 29), and 4) seropositive offspring born to seropositive dams (n = 30). The birth weight, survival, reproductive performance and abortion of these offspring were studied from birth to culling. Maternal seropositivity was positively associated with offspring seropositivity (P < 0.05). Birth weight did not differ among offspring in various categories (P > 0.05). Seropositive offspring born to seronegative dams and seronegative offspring born to seropositive dams had inferior cumulative reproductive performance over life as compared to seronegative offspring born to seronegative dams (P < 0.05). Seropositive offspring had greater cumulative abortion risk and shorter lifespan than seronegative offspring regardless of their maternal serologic condition (P < 0.05). In conclusion, the present study showed that maternal seropositivity for N. caninum increased the risk of seropositivity in the offspring, and seropositive offspring had increased abortion risk and decreased longevity. Maternal seropositivity for N. caninum could have developmental effects on cumulative reproductive performance of the offspring that were not vertically infected.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Veterinary parasitology, regional studies and reports Multiple-

CiteScore

2.90

自引率

7.10%

发文量

126

审稿时长

97 days

期刊介绍： Veterinary Parasitology: Regional Studies and Reports focuses on aspects of veterinary parasitology that are of regional concern, which is especially important in this era of climate change and the rapid and often unconstrained travel of people and animals. Relative to regions, this journal will accept papers of the highest quality dealing with all aspects of disease prevention, pathology, treatment, epidemiology, and control of parasites within the field of veterinary medicine. Also, case reports will be considered as they add to information related to local disease and its control; such papers must be concise and represent appropriate medical intervention. Papers on veterinary parasitology from wildlife species are acceptable, but only if they relate to the practice of veterinary medicine. Studies on vector-borne bacterial and viral agents are suitable, but only if the paper deals with vector transmission of these organisms to domesticated animals. Studies dealing with parasite control by means of natural products, both in vivo and in vitro, are more suited for one of the many journals that now specialize in papers of this type. However, due to the regional nature of much of this research, submissions may be considered based upon a case being made by the author(s) to the Editor. Circumstances relating to animal experimentation must meet the International Guiding Principles for Biomedical Research Involving Animals as issued by the Council for International Organizations of Medical Sciences (obtainable from: Executive Secretary C.I.O.M.S., c/o W.H.O., Via Appia, CH-1211 Geneva 27, Switzerland).