艾滋病病毒感染者的严重贫血：人口、临床和肾脏相关性。

IF 1.6 Q2 MULTIDISCIPLINARY SCIENCES

BMC Research Notes Pub Date : 2025-02-03 DOI:10.1186/s13104-025-07100-x

Kingsley Kamvuma, Sody Munsaka, Sepiso K Masenga, John Amos Mulemena, Christopher Newton Phiri, Michelo Miyoba, Benson M Hamooya

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Severe anaemia in people with HIV: demographic, clinical and renal correlates.

Objective: This study aimed to investigate the sociodemographic, clinical and renal correlates associated with severe anaemia among people with HIV.

Methods: We conducted a cross-sectional analysis of people with HIV on antiretroviral therapy (ART) for at least 6 months, stratified by anaemia status. Anaemia was defined based on the World Health Organisation (WHO) classification, as haemoglobin concentration lower than normal i.e. <12 g/dl in females and < 13 g/dl in males and the primary outcome, severe anaemia, as a haemoglobin level below 8 g/dl according to the World Health Organisation.

Results: The study comprised 372 participants receiving ART, of whom 236 (63.4%) were females. The mean age ± SD of the participants was 44.8 ± 12.4 years. The overall prevalence of severe anaemia was 7.8% (95% CI: 0.053-0.111). In multivariable logistic regression analysis, factors significantly associated with severe anaemia were female sex (Adjusted Odds Ratio (AOR: 14.3, 95% CI: 2.14-126.6), albumin (AOR: 0.93 95% CI: 0.88-0.98) and creatinine levels (AOR: 1.01 95% CI: 1.00-1.03).

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来源期刊

BMC Research Notes Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

3.60

自引率

0.00%

发文量

363

审稿时长

15 weeks

期刊介绍： BMC Research Notes publishes scientifically valid research outputs that cannot be considered as full research or methodology articles. We support the research community across all scientific and clinical disciplines by providing an open access forum for sharing data and useful information; this includes, but is not limited to, updates to previous work, additions to established methods, short publications, null results, research proposals and data management plans.